The activity of Cdc25-like proteins is a rate-limiting step in Drosophila cell cycles as the string and twine phosphatases derepress the Cyclin-dependent kinase Cdk1 to initiate the G2/M transition. Surprisingly, overexpression of string causes cysts to form with only eight cystocytes, in ...
Hippo信号通路在进化中高度保守,当细胞处于高密度生长或营养缺乏的环境中时,Hippo信号通路即被激活,MST激酶(mammalian sterile 20-like kinase)被磷酸化,在MOB1(Mps One Binder kinase activator protein 1,Mps一结合者激酶激活因子样1)蛋白的辅助...
Epithelial-to-mesenchymal transition (EMT) is a process by which epithelial cells acquire motile and invasive properties, characteristic of mesenchymal-like cells.13 EMT occurs naturally in development; however, it can be inappropriately exploited during carcinogenesis to augment oncogenic transformation of...
CCNB1, G2/mitotic-specific cyclin-B1, G2/mitotic specific cyclin B1, Cyclin B, CCNB Formulation: PBS and Azide PBS and Azide Conjugate: Unconjugated Unconjugated CoraLite® Plus 488 Size: 50 μL 100 μL 150 μL ¥2200/ 100 μL 浓度: 500 ug/ml 库存:现货 收藏 点击咨询售前客服...
Epithelial ovarian cancer (EOC) has the highest mortality rate among gynecological malignancies owing to poor screening methods, non-specific symptoms and limited knowledge of the cellular targets that contribute to the disease. Cyclin G2 is an unconvent
Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7. Mol Biol Cell 2008; 19:4968- 4979.Xu G, Bernaudo S, Fu G, Lee D, Yang B, Peng C. Cyclin G2 is degraded through the ubiquitin- proteasome pathway ...
Inflammatory Fibroblast-Like Synoviocyte-Derived Exosomes Aggravate Osteoarthritis via Enhancing Macrophage Glycolysis Authors - Bin Liu View Article mouse WB Acta Pharm Sin B The substitution of SERCA2 redox cysteine 674 promotes pulmonary vascular remodeling by activating IRE1α/XBP1s pathway. Authors ...
Epithelial ovarian cancer (EOC) has the highest mortality rate among gynecological malignancies owing to poor screening methods, non-specific symptoms and limited knowledge of the cellular targets that contribute to the disease. Cyclin G2 is an unconvent
In tumor immunity, IFN-γ-activated M1-like mac- rophages can enhance the antitumor effect of cytotoxic T lymphocytes (CTLs) [6], and macrophages activated by IFN-γ can inhibit tumor angiogenesis by regulating cytokine secretion [7]. However, mechanisms of IFN-γ activated macrophages on ...
2-10 µg/mg lysate - 产品规格 种属反应 Human 宿主/亚型 Rabbit / IgG 分类 Polyclonal 类型 Antibody 抗原 Region between residue 382 to 432 of human Cyclin-A2. 查看免疫原 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型 Antigen affinity chromatography ...