将creERT2-WPRE-polyA插入到小鼠Cx3cr1基因起始密码子处。 应用领域:Cre工具鼠,单核吞噬细胞等区域 *使用本品系发表的文献需注明: Cx3cr1-CreERT2 mice (Cat. NO. NM-KI-200157) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 图1 Cx3cr1CreERT2/+; Rosa26tdTomato/+小鼠...
C-X3-C motif chemokine receptor 1 (CX3CR1) is a Gαi-coupled seven-transmembrane protein exclusively expressed in the mononuclear phagocyte system including microglia [7]. In adultCx3cr1CreERT2mice, Cre activity–dependent tamoxifen (TAM)-inducible gene recombination is possible in CX3CR1+mac...
Cx3cr1CreERT2 mice express Cre recombinase in a tamoxifen-inducible manner and have been widely used to delete target genes in microglia, since microglia are long-lived cells and outlive peripheral macrophages, which continuously turn over and lose their gene modification over time. ATG7 is an ...
Cx3cr1CreERT2 mice express Cre recombinase in a tamoxifen- inducible manner and have been widely used to delete target genes in microglia, since microglia are long-lived cells and outlive peripheral macrophages, which continuously turn over and lose their gene modification over time. ATG7 is an...
*使用本品系发表的文献需注明: Cx3cr1-2A-tdTomato-IRES-CreERT2 mice (Cat. NO. NM-KI-242749) were purchased from Shanghai Model Organisms Center, Inc.. 相关品系 Cx3cr1-Flox 品系名:C57BL/6Smoc-Cx3cr1em1(flox)Smoc 品系状态:活体 | 目录号:NM-CKO-226496 ...
Cx3cr1CreERT2 mice express Cre recombinase in a tamoxifen-inducible manner and have been widely used to delete target genes in microglia, since microglia are long-lived cells and outlive peripheral macrophages, which continuously turn over and lose their gene modification over time. ATG7 is an ...
Temporal genetic labeling (Cx3cr1-CreERT2;R26-tdTomato) showed that CX3CR1+ cells at E6.5 can contribute to cardiomyocytes (CMs) and endothelial cells (ECs) during prenatal development via both de novo differentiation and fusion with pre-existing CMs or ECs, respectively. In the adult heart...
Mouse: Cx3cr1-CreER: B6.129P2(Cg)-Cx3cr1tm2.1(cre/ERT2)Litt/WganJ The Jackson Laboratory RRID: IMSR_JAX:021160 Mouse: Gpr35-tdTomato: Gpr35 < tm1.1Niess > Mouse Genome Informatics Jackson Laboratory MGI:6436879 Mouse: Gpr35−/−: Gpr35 < em1Niess > Mouse Genome Informatics Jacks...
RESULTS: Histological and expression profiles of CCM neurovascular lesions (Slco1c1-iCreERT2;Pdcd10fl/fl; Pdcd10BECKO ) in male and female mice found that sustained mild hypoxia (12% O2, 7 days) accelerates CCM disease. Our findings indicate that a small reduction in oxygen levels can ...
*使用本品系发表的文献需注明: Cx3cr1-2A-tdTomato-IRES-CreERT2 mice (Cat. NO. NM-KI-242749) were purchased from Shanghai Model Organisms Center, Inc.. 相关品系 Cx3cr1-Flox 品系名:C57BL/6Smoc-Cx3cr1em1(flox)Smoc 品系状态:活体 | 目录号:NM-CKO-226496 ...