一文梳理:Cushing综合征的诊断与治疗 | 临床实战 导读:Cushing综合征(Cushing syndrome,CS,库欣综合征),又称皮质醇增多症,是以慢性高皮质醇血症为特征的临床综合征,主要表现为满月脸、多血质外貌、向心性肥胖、痤疮、紫纹、高血压、继发性糖尿病和骨质疏松...
Guignat L,Bertherat J.The diagnosis of Cushing’’s syndrome: an Endocrine Society Clinical Practice Guideline: commentary from a European perspective. European Journal of Endocrinology . 2010Guignat L, Bertherat J. The diagnosis of Cushing's syndrome: an Endocrine Society Clinica...
Cushing综合征(Cushing syndrome,CS),又称皮质醇增多症,是以慢性高皮质醇血症为特征的临床综合征,主要表现为满月脸、多血质外貌、向心性肥胖、痤疮、紫纹、高血压、继发性糖尿病和骨质疏松等。Cushing综合征的病因可分为ACTH依赖性和ACTH非依赖性两类。 一、问诊要点 1.注意询问患者有无诱因,如长期使用糖皮质激素类...
The new document is the first from the society to address treatment of Cushing's syndrome, which is characterized by an excess of the hormone cortisol in the blood, which is usually caused by a tumor. Previous guidelines addressed diagnosis. Normalize Cortisol Levels and Then Individualize Treatmen...
Endogenous Cushing's syndrome (CS) is a rare disease, and usually characterized by hypertension, diabetes, obesity, osteoporosis, facial rounding, dorsocervical fat pad, thin skin, purple striae, hirsutism, and mood disorders. Efficient diagnostic and screening strategies lead to the diagnosis of a...
OBJECTIVE: To evaluate which tests are performed to diagnose hypercortisolism in patients included in the European Registry on Cushing's syndrome (ERCUSYN), and to examine if their use differs from the current guidelines. PATIENTS AND METHODS: We analyzed data on the diagnostic tests performed in...
The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2-2% and it may no longer be considered as an orphan disease (2-3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment....
[摘要] 目的 分析Cushing综合征患者的不同病因、临床表现及内分泌实验室检查和影像学检查的特点,评价各种病因鉴别诊断方法的效率。方法 对经手术病理确诊为Cushing综合征的42例患者的临床资料和实验室检查、影像学检查等资料进行回顾分析。结果 42例患者的病因以Cush
The key biochemical features of Cushing syndrome consist of excessive endogenous secretion of cortisol, loss of the normal feedback of the HPA axis, and disturbance of the normal circadian rhythm ofcortisol secretion. Recent guidelines on the diagnosis of Cushing syndrome recommend using at least two...
Diagnosis of Cushings-SyndromeCaduff, FStaub, J JNordmann, ARadu, E WLandolt, H