Prolonged exposure of every tissue in the body to an excess to an excess of cortisol produces Cushing's syndrome. Endogenous causes of Cushing's syndrome are ACTH-dependent, including Cushing's disease, ectopic ACTH-producing tumors, CRH-producing tumors, and ACTH-independent Cushing's syndrome, ...
Diagnosis of Cushings-SyndromeCaduff, FStaub, J JNordmann, ARadu, E WLandolt, H
(2007) Specificity of first-line tests for the diagnosis of Cushing's syndrome. Assessment in a large series. J Clin Endocrinol Metab 92: 4123-4129 SYNOPSIS BACKGROUND Laboratory diagnosis of Cushing's syndrome requires the use of tests with high sensitivity; however, reduced diagnostic thresholds...
But in a recentinterview with "News Not Noise" blogger Jessica Yellin,Schumer said after reading the comments she was diagnosed with Cushing syndrome, whichaccording to the Mayo Clinicoccurs when the body has too much of the hormone cortisol over a long period of time. What is Cushing ...
[摘要] 目的 分析Cushing综合征患者的不同病因、临床表现及内分泌实验室检查和影像学检查的特点,评价各种病因鉴别诊断方法的效率。方法 对经手术病理确诊为Cushing综合征的42例患者的临床资料和实验室检查、影像学检查等资料进行回顾分析。结果 42例患者的病因以Cush
Spontaneous Cushing's syndrome is well known but unusual clinical disorder. Many of the clinical features (central weight gain, glucose intolerance, hypertension, muscle weakness) are seen in other common conditions. Recognition of patients with multiple features, features unusual for their age (i.e...
Urine free cortisol in the high-dose dexamethasone suppression test for the differential diagnosis of the Cushing syndrome. Ann Intern Med. 1992;116:211–7. Findling JW, Doppman JL. Biochemical and radiologic diagnosis of Cushing’s syndrome. Endocrinol Metab Clin North Am. 1994;23:511–37. ...
For the conclusive diagnosis of Cushing's Syndrome, a stimulating ACTH test or a low suppressive Dexamethasone test is used. Reports in other species than the dog indicate that plasma cortisol concentration after ACTH administration is affected by gender. We investigated the effect of gender on the...
Endogenous Cushing's syndrome (CS) is a rare disease, and usually characterized by hypertension, diabetes, obesity, osteoporosis, facial rounding, dorsocervical fat pad, thin skin, purple striae, hirsutism, and mood disorders. Efficient diagnostic and screening strategies lead to the diagnosis of a...
Cushing's syndrome and its various aetiologies is a markedly difficult diagnosis to make given its subtle signs, sometime cyclical nature, and the lack of a single definitive diagnostic test. Although a great variety of diagnostic tests have been developed to assist in the diagnosis, even with ...