Purpose No consensus exists as the gold standard for Cushing's Syndrome (CS) screening. This study aimed to evaluate the diagnostic accuracy and utility of late-night salivary cortisol (LNSC) and cortisone (LNSE), overnight dexamethasone suppression test (ODST), and urinary free cortisol (UFC)...
The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2-2% and it may no longer be considered as an orphan disease (2-3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment....
Endogenous Cushing's syndrome (CS) is a rare disease, and usually characterized by hypertension, diabetes, obesity, osteoporosis, facial rounding, dorsocervical fat pad, thin skin, purple striae, hirsutism, and mood disorders. Efficient diagnostic and screening strategies lead to the diagnosis of a...
Differentiating ACTH-Dependent from ACTH-Independent Cushing’s Syndrome ACTH-Dependent Cushing’s Syndrome Ectopic ACTH Syndrome ACTH-Independent Cushing’s Syndrome Algorithm for Cushing’s Syndrome Differential Diagnosis (Fig. 7.6) References References Other actions Reprints and Permissions Expo...
Diagnosis of Cushings-SyndromeCaduff, FStaub, J JNordmann, ARadu, E WLandolt, H
Understanding this system is required to master the diagnosis, differential diagnosis and treatment of endogenous hypercortisolism – Cushing's syndrome. Endogenous Cushing's syndrome is caused either by excess ACTH secretion or by autonomous cortisol release from the adrenal cortex. Diagnosis of ...
Cushing’s Syndrome Diagnosis It might take several appointments to settle on your diagnosis. When you go to your doctor, they'll do aphysical examand ask you questions, such as: What symptoms have you noticed? When did you first see them?
a female patient with cyclical Cushing's syndrome illustrates how recent advances such as the introduction of the corticotropin-releasing hormone (CRH) test (in determining the cause of ACTH production) and high-resolution computed tomographic scanning may help in the diagnosis of Cushing's syndrome....
Diagnostic algorithm for screening and differential diagnosis of cushing syndrome in paediatric population Imaging Pituitary magnetic resonance imaging (MRI) Since ACTH-secreting pituitary adenomas are very small (usually < 6 mm in diameter), it is difficult to localize these tumours. Diagnostic work...
Results Cushing′s disease was the most common cause of Cushing′s syndrome. About 64.3% patients had typical Cushing symptoms. The prevalence of glucose intolerance and hypertension were 61.9% and 61.9%, respectively. The sensitivity for diagnosis from high to low was lack of cortisol suppression...