In contrast, all other drugs (e.g., LSD, barbiturates, amphetamines) were used by a relatively small proportion of respondents and typically in an "experimental" fashion; i.e., used on only one or two occasions with no intention for future use. The relationship of various demographic, ...
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Still, these studies are necessary to examine the persistent effects of ecstasy use. Method: 30 current and 31 previous users of ecstasy with concomitant use of amphetamine, cannabis, cocaine and LSD and 24 pure cannabis users were compared on a battery of neuropsychological tests and on ...
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approximately 61.2 million people had OA in 2017.7Despite the high prevalence, no disease-modifying drugs are currently available. The prescription drugs recommended by international guidelines for OA management merely provide pain relief for symptoms, and the long-term use of these drugs is often asso...
use of analytical platforms28are important to handle inter- and intra-patient tumor heterogeneity. This requires a deep understanding but also a panoramic grasp of the current knowledge of mechanisms of anti-tumor immunity as well as of established and potential therapeutic targets and immunomodulatory...
Considering the synergistic effect of radiotherapy and DDR inhibitors in promoting DNA damage, the use of DDR inhibitors to maintain radiotherapy-induced immune responses is a feasible strategy. While LDRT causes the release of dsDNA, activating the cGAS-STING pathway to promote innate immunity and ...
In electric vehicles, recirculating air presents a bigger challenge, as many EVs use an HVAC system’s recirculation function to maintain efficiency and conserve energy. It takes less energy to heat or cool recirculated air than it does to heat or cool “fresh” outside air using an HVAC sys...
The safety profiles, patient responses, and analgesic properties of these compounds are examined, highlighting the need for further research to validate their efficacy and optimize their therapeutic use in pain management. Authors and Affiliations ...
assisted psychotherapy for depression, including previously treatment-resistant symptoms. MDMA-assisted psychotherapy is showing similar promise in treating PTSD, with excellent response and remission rates that appear durable. However, no studies have looked at the use of these treatments in younger ...