Cure for Type 1 diabetes imminent after Harvard stem-cell breakthroughhereTelegraph
In 2017 researchers kicked off a Phase 1/2 human clinical trial testing an experimental implant designed to replace the missing insulin cells in type 1 diabetics. The device has been described as a “functional cure” for type 1 diabetes. This means it isn’t a direc...
In type 1 diabetes we have two problems. There is an absence of insulin-producing beta cells and also an autoimmune attack, which is what killed the cells in the first place. Our lab and others have worked on problem one and I am confident that we are going to get buckets of beta cel...
Science could be well on its way to a cure for type 1 diabetes, as researchers hone transplant therapies designed to restore patients' ability to produce their own insulin, experts say.
A study has demonstrated that transplanting human embryonic stem cell–derived, insulin-producing cells shielded in capsules made with an optimized biomaterial can achieve long-term cure of diabetes in mice without the need for any immunosuppression. This is a preview of subscription content, log in...
Those of us in the field of diabetes have long wanted to curetype 1 diabetes, and there are little steps making me feel like this might be a possibility. One of those steps is that a company named Vertex — I'm actually on the steering committee for Vertex in terms of this project —...
Narrator:Peter Hansell is 68. A few years ago, he was diagnosed with type 2 diabetes. Peter Hansell:When I was diagnosed, I didn’t think it would have the restrictions it had on my life, it just wasn’t s...
Insulin has been the gold standard therapy for diabetes since its discovery and commercial availability. It remains the only pharmacologic therapy for type 1 diabetes (T1D), an autoimmune disease in which autoreactive T cells specifically kill the insulin-producing beta cells. Nevertheless, not...
Tight glycaemic control in type 1 diabetes mellitus has been shown to be important for the prevention of long-term microvascular complications. Consequently, intensive insulin treatment has been advocated in the attempt to achieve normal glycaemia. This has proven challenging mainly due to an increased...
Researchers from the Universitat Autònoma de Barcelona (UAB), led by Fàtima Bosch, have shown for the first time that it is possible to cure diabetes in large animals with a single session of gene therapy. As published this week in Diabetes, the princi