New research may lead to cure for type 1 diabetesDay Greenberg
at the Harvard Stem Cell Institute in Cambridge, Massachusetts, reported the first successful generation of insulin-producing cells from the skin cells of people with type 1 diabetes.Roger Highfieldspoke to Melton about the personal driving force behind his research, and where he sees work on stem...
"The present study demonstrates definitively for the first time to our knowledge, in a small number of human subjects with type 1 diabetes, that PSC-derived pancreatic progenitor cells have the capacity to survive, engraft, differentiate, and mature into human islet-like ...
Nearly 50years after the autoimmune nature of type 1 diabetes was discovered, no therapy has been approved to alter the course of the disease at any stage. However, during that same period, technology has been delivering tools to help patients achieve better glycemic control and reduce the ...
As Fàtima Bosch, the head researcher, points out, "this study is the first to demonstrate a long-term cure for diabetes in a largeanimal modelusing gene therapy." This same research group had already tested this type of therapy on mice, but the excellent results obtained for the first tim...
Johnson & Johnson, continuing its long quest for a Type 1 diabetes cure, is joining forces with biotech company ViaCyte to speed development of the first stem cell treatment that could fix the life-threatening hormonal disorder. They've already begun testing it in a small number of dia...
Although the exact cause of type 1 diabetes isn’t known, it’s thought to be caused by an autoimmune response where the body attacks and destroys the pancreas’ beta cells, the cells that produceinsulin. For years, researchers have looked at‘curing’ diabetesby using stem cells to createin...
The article reports that after being subjected to years of disbelief and derision by the scientific community, scientist Denise Faustman's research on a cure for diabetes has been backed by three studies. Faustman found that mice with Type-1 diabetes could be cured by stopping their immune syst...
Looking ahead, the FDAhas approveda similar cell therapy developed by a Chicago-based startup for type 1 diabetes, showing a growing interest in this approach. However, Chinese researchers emphasize the need for further studies to confirm the long-term efficacy and broader applicability of their ...
CureDM, Inc. is a biopharmaceutical company established to develop new therapies that may prevent, ameliorate or reverse diabetes and allow for the discontinuation of insulin. Theresearch teamat CureDM has discovered and is developing a novel human peptide associated with regeneration of insulin-produc...