Signal peptide-CUB-EGF domain-containing protein 1(SCUBE1)levels in patients with overt and subclinical hyperthyroidism:effects of treatment [J]. Clin Endocrinol(Oxf), 2015, 16(9): 458-63.EREM C,CIVAN N,COSKUN H,et al.Signal peptideCUB-EGF domain-containing protein 1(SCUBE1)levels in ...
(2008) CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am. J. Pathol. 172, 1729 -1739Uekita, T.; Tanaka, M.; Takigahira, M.; Miyazawa, Y.; Nakanishi, Y.; Kanai, Y.; Yanagihara, K.; Sakai, R. CUB-domain-containing protein 1 ...
Background Deregulated expression of the transmembrane glycoprotein CDCP1 (CUB domain-containing protein-1) has been detected in several cancers including colon, lung, gastric, breast, and pancreatic carcinomas. CDCP1 has been proposed to either positively or negatively regulate tumour metastasis. In ...
E Lezan1, M Bentires-Alj3, H Voshol1, D Bonenfant1,4 and L Alex Gaither2,4 The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor prognosis for patients on standard...
摘要 背景:信号肽-CUB-表皮生长因子样结构域蛋白(signal peptide-CUB-EGF-like domain-containing protein,SCUBE)可作为辅助受体和/或配体激 活骨形态发生蛋白,血管内皮生长因子,转化生长因子β和刺猬因子等信号通路,在多种生理和病理过程中扮演着重要的角色. 目的:综述国内外相关文献,总结SCUBE家族成员的结构与功能,...
The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor prognosis for patients on standard of care therapies. Phosphorylation of CDCP1 ty
VHLloss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKCδ-driven migration A common genetic mutation found in clear cell renal cell carcinoma (CC-RCC) is the loss of the von Hippel-Lindau (VHL) gene, which results in stabilization... Olga...
The antibody against the SP domain also detected two bands that were approximately 58 and 25 kDa (Fig. 3A), suggesting that the CUB and SP domains might be expressed as a single protein and then separated by cleavage at Ile-324 in Aa-CUB-SP. Among the developmental stages of A. ...
The transmembrane glycoprotein, CUB domain-containing protein 1 (CDCP1) has been reported to be up-regulated in various cancers, and be associated with invasion and metastasis. The aim of this study was to examine the effect of AHCC on the expression of CDCP1 in KLM1-R cells. Materials ...
24 Abstract 25 Background: Deregulated expression of the transmembrane glycoprotein CDCP1 (CUB 26 domain-containing protein-1) has been detected in several cancers including colon, lung, 27 gastric, breast, and pancreatic carcinomas. CDCP1 has been proposed to either positively 28 or negatively ...