OBJECTIVES: Recently, a CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli O25b-ST131 clone, belonging to the B2 phylogenetic grou... C Olivier,D Hiran,U Mathew,... - 《Journal of Antimicrobial Chemotherapy》 被引量: 664发表: 2009年 Virulence factors in Escherichia ...
摘要: CTX-M-15是一种同时具备水解头孢噻肟和头孢他啶能力的超广谱β-内酰胺酶,目前在世界各地广泛,快速的传播,甚至在局部地区出现暴发流行.本文就CTX—M-15酶的分子特点,流行病学及CTX-M-15编码基因(blaCTX-M-15)及其基因环境等研究方面作一综述.关键词: CTX-M-15;传播机制;基因环境;研究进展 ...
CTX-M-15 extended-spectrum β-lactamase in a shiga toxin-producing Escherichia coli isolate of serotype O111:H8. Valat, Charlotte,Haenni, Marisa,Saras,... Valat,Charlotte - 《Applied & Environmental Microbiology》 被引量: 49发表: 2012年 Virulence properties and characteristics of Shiga toxin-...
Two CTX-M-type genes were sequenced and had amino acid sequences indistinguishable from previously sequenced CTX-M-15 beta-lactamases. The ISEcp1 element was located upstream of bla(CTX-M-15) in the same position as previously described. In addition, 23 of the isolates produced TEM beta-...
— CTX-M beta-lactamases are enzymes were named for their greater activity against cefotaxime than other oxyimino-beta-lactam substrates (e.g., ceftazidime, ceftriaxone, or cefepime). The main aim of this study was to determine CTX-M-15 in gram-negative bacteria isolated from Afghaninan refuge...
In this study, we have identified a CTX-M-15-producing Shewanella species that was responsible for a hepatobiliary infection and that is likely the progenitor of OXA-436, a novel plasmid-encoded OXA-48-like class D carbapenemase. 展开
另外一些基因型流行范围较小,如 OXA、PER、GES、VEB 和 SFO 等基因型。不同地区流行的基因亚型也有差异,在欧洲国家 CTX-M-15 检出率最高,其次是 CTX-M-14,在非洲和澳大利亚地区,CTX-M-15 占大多数,在亚洲,CTX-M-14 和 SHV-12 流行较广。
检出CTX-M-15酶基因,检出率分别为78.6%和50.0%;携带CTX-M-14与CTX-M-15酶基因的多药耐药大肠埃希菌对头孢噻肟,头孢他啶的耐药率分别81.8%,52.2%和96.4%,60.7%,两者相比较,差异有统计学意义(P0.01).结论多药耐药大肠埃希菌中,含CTX-M-14与CTX-M-15酶基因菌株是常见的,携带CTX-M-14与CTX-M-15酶基因...
进行研究.结果 447株产ESBLs菌株中筛选到1株产armA型16S rRNA甲基化酶的产酸克雷伯菌(ZJ157),并在该菌株中同时检出CTX-M-15型ESBLs和TEM-1型β-内酰胺酶... 沈晓强,周华,季淑娟,... - 《中华临床感染病杂志》 被引量: 10发表: 2010年 河南省奶牛乳腺炎中肺炎克雷伯菌的流行特征与耐药性研究 奶牛乳...