不同地区流行的基因亚型也有差异,在欧洲国家 CTX-M-15 检出率最高,其次是 CTX-M-14,在非洲和澳大利亚地区,CTX-M-15 占大多数,在亚洲,CTX-M-14 和 SHV-12 流行较广。 产ESBLs 大肠埃希菌的定植 产ESBLs 的大肠埃希菌在抗生素的选择压力下,成为优势菌株积累...
结果:等电聚焦电泳表明供体菌携带的β内酰胺酶的PI分别为8.8(CTX-M-15)、8.2(SHV-12)、7.8(DHA-1)、5.4(TEM-1);接合实验表明耐药基因CTX-M-15,SHV-12,TEM-1,DHA-1,qnrB可以通过结合作用转移给受体菌;供体菌体外对头孢噻肟、头孢他啶、头孢西丁和环丙沙星的MIC分别是128、128、128和128mg/L;质粒电泳...
OBJECTIVES: Recently, a CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli O25b-ST131 clone, belonging to the B2 phylogenetic grou... C Olivier,D Hiran,U Mathew,... - 《Journal of Antimicrobial Chemotherapy》 被引量: 662发表: 2009年 The CTX-M-15-producing Escheric...
目的了解多药耐药大肠埃希菌携带质粒介导的CTX-M-14与CTX-M-15酶基因分布及其对常见抗菌药物的耐药性,为临床合理选择抗菌药物提供依据。方法收集2007年7月-2008年7月感染患者送检标本中分离出的大肠埃希菌71株,采用纸片扩散法(K-B法)对其中多耐30株、双耐19株及单耐16株大肠埃希菌进行药物敏感试验,提取质粒DNA,...
Infection and Drug Resistance Dovepress open access to scientific and medical research Open Access Full Text Article ORIGINAL RESEARCH CTX-M-15 Positive Escherichia coli and Klebsiella pneumoniae Outbreak in the Neonatal Intensive Care Unit of a Maternity Hospital in Ha'il, Saudi Arabia Mohammed ...
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Among 603 isolates of Enterobacteriaceae collected between June and November 2003 from three university hospitals within Korea, bla(CTX-M-3), bla(CTX-M-15), bla(CTX-M-14), and bla(CTX-M-9) were detected in 41 isolates of species from five different genera of Enterobacteriaceae, Escherichia...
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M-15, and find three non-synonymous mutations with increased resistance against mecillinam or piperacillin–tazobactam that simultaneously confer full susceptibility to several cephalosporin drugs. We show in vitro and in mice that a combination of mecillinam and cefotaxime eliminates both wild-type ...