Abatacept 是选择性 T 细胞共刺激调节剂,也是一种用于自身免疫性疾病的蛋白活性分子。 生物活性:阿巴西普 (CTLA4lg) 是一种可溶性融合蛋白,由人 CTLA4 的细胞外结构域和人 IgG1 的 Fc 部分片段(铰链和 CH2 和 3 结构域)组成[1]。阿巴西普是一种选择性 T 细胞共刺激调节剂,也是一种治疗自身免疫性疾病的蛋...
CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice. Takiguchi M,Murakami M,Nakagawa I,et al. Life Sciences . 2000Takiguchi M,Murakami M,Nakagawa I,et al.CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice.Life ...
CTLA4-IgG是呈分泌性表达的CTLA4胞外区与人IgG恒定区的融合分子,可有效阻断T细胞B7-CD28共刺激信号通路,从而抑制T细胞活化,延长移植物存活.糖尿病溃疡创面难愈合是其高致病力和高致残率的主要原因,而及时有效的封闭创面是创面...
产品编号: hctla4-mab12 品牌: Invivogen 规格: 100 µg 产品介绍 服务承诺 订货流程 相关产品推荐 InvivoGen于1997年成立于法国,致力于天然免疫相关产品的研发和生产, InvivoGen公司提供各类PRRs(模式识别受体)相关的全套产品,包括PRRs配体(激动剂和拮抗剂)、PRRs诱导剂和抑制剂、报告细胞系、抗体和基因;另...
产品编号: hctla4-mab13 品牌: Invivogen 规格: 100 µg 产品介绍 服务承诺 订货流程 相关产品推荐 InvivoGen于1997年成立于法国,致力于天然免疫相关产品的研发和生产, InvivoGen公司提供各类PRRs(模式识别受体)相关的全套产品,包括PRRs配体(激动剂和拮抗剂)、PRRs诱导剂和抑制剂、报告细胞系、抗体和基因;另...
ChemicalBook provide Chemical industry users with Anti-hCTLA4-hIgG4 (S228P)抗体 Boiling point Melting point,Anti-hCTLA4-hIgG4 (S228P)抗体 Density MSDS Formula Use,If You also need to Anti-hCTLA4-hIgG4 (S228P)抗体 Other information,welcome to contact us.
【目的】探讨细胞毒性T淋巴细胞相关抗原4免疫蛋白(cytotoxicity T lymphocyte-associated 4-immunoglobulin G,CTLA4-IgG)对同种异体大鼠胰腺移植排斥反应的影响。 Objective : To evaluate the effect of C...
pertains to isolated CTLA4-immunoglobulin fusion proteins comprising a first peptide having a CTLA4 activity and a second peptide comprising an immunoglobulin constant region which is modified to reduce at least one constant region-mediated biological effector function relative to a CTLA4-IgG1 fusion ...
Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis. Pediatr Nephrol. 2015;30:469–77. : 10.1007/s00467-014-2957-6 .Garin EH, Reiser J, Cara-Fuentes G, Wei C, Matar D, Wang H, Alachkar N, Johnson RJ (2015) Case series: CTLA4-...
Using CTLA4IgG, we examined induction of long-term graft survival and the mechanism of maintenance of tolerance in rat allogeneic small bowel transplantation.Methods.Small bowels of Brown-Norway rats (RT1n) were heterotopically transplanted into Lewis rats (RT11). Recipients were treate...