In CT26, we found the Kras G12D mutation and no expression of Egfr. Consistent with this, CT26 cells have been shown to be refractory to the rodent Egfr-targeting mAbs [2]. Similarly, KRAS G12D mutations and MAPK1 (MEK) and MET amplification are published biomarkers for colorectal tumor...
(5812):642-645. statusand inmetastatic EGFR—targetedtherapies CRC[J].Nat V.Wilmstumor [2]RuteshouserECl,RobinsonSM,Huff genetics: RevClin Oncol,2009,6(9):519-527. in CTNNBl for about mutations account WTl,删,and only [17]Shi WZ,YanLB,et and of H,Wang a1.Expressionsignificance Genes...
At the end of the experiment, serum biochemical, T cell immunophenotyping, serum cytokine, histopathology of tumour and organ section, TUNEL assay, and Nanostring gene expression analysis were performed. Results The rAF-IL12 induced apoptosis of CT26 colon cancer cells in vitro as revealed in the...
At the end of the experiment, serum biochemical, T cell immunophenotyping, serum cytokine, histopathology of tumour and organ section, TUNEL assay, and Nanostring gene expression analysis were performed. Results The rAF-IL12 induced apoptosis of CT26 colon cancer cells in vitro as revealed in the...