英文名称: 总访问: 1905 国产/进口: 国产 半年访问: 80 产地/品牌: 南模生物 产品类别: 实验动物 规格: Csf1r-(IRES-iCre)小鼠Cre活性验证 最后更新: 2025-2-26 货号: 参考报价: 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:微信新浪微博销售商: 上海南方模式...
将IRES-iCre共表达结构插入到小鼠Csf1r基因终止密码子处。 应用领域:Cre工具鼠 *使用本品系发表的文献需注明: Csf1r-IRES-Cre mice (Cat. NO. NM-KI-190026) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 图1.流式检测Csf1r-Cre+/-;R26-mTmG+/-小鼠外周血巨噬细胞中荧光基因的...
作者分别在缺乏P53(PDG-p53 KD)和Ink4a/Arf(PDG-Ink4a/Arf KO)抑癌基因小鼠胶质瘤模型中进行分割放疗(2Gy/天,5天共10Gy);通过使用Flt3:Cre和Rosa26:mTmG髓系细胞谱系追踪模型。在该模型中,外周募集的MDM呈绿色荧光蛋白阳性(green fluorescent protein–positive,GFP+),而来自卵黄囊前体的MG呈GFP−,产生Frce。
与R26R~(EYFP)组比较,Csf1r-Cre~(ERT2)小鼠介导EYFP标记效率最高的是脑组织(P<0.001),最低的是胸腺组织(P<0.05),脾脏组织则差异无统计学意义.结论 成年Csf1r-Cre~(ERT2)小鼠与R26R~(EYFP)小鼠是获得Csf1r-Cre~(ERT2) R26R~(EYFP)诱导型条件性荧光小鼠的有效途径.Csf1r-Cre~(ERT2)介导EYFP可对小鼠...
To test the hypothesis, we created a hematopoietic calcium reporter mouse (Csf1r-Cre x GCaMP5) and non-destructively quantified the spatiotemporal dynamics of intracellular calcium in vitro and in vivo. In vitro, bone marrow derived macrophages calcium reporters reveal that fatal immune stimulatory ...
值得注意的是,这项研究还为开发米诺环素作为小胶质细胞稳态调节剂,治疗患有ALSP发病高风险的CSF1R突变患者提供了强有力的治疗基础。
The numbers of lysozyme-expressing Paneth cells were unchanged in the intestinal crypts of Csf1rΔIEC mice compared to Vil1-Cre and Csf1rFL/FL transgenic control mice (Fig. 3g, h). Paneth cell morphology and expression of Defa1 were also unaffected in the intestines of Csf1rΔIEC mice (...
Csf1r-IRES-Cre 品系名:C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc 品系状态:精子冻存 | 目录号:NM-KI-190026 hCSF1/hCSF1R(BALB/c) 品系名:BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc 品系状态:胚胎冻存 | 目录号:NM-HU-220016 Csf1-Flox 品系名:C57BL/6Smoc-Csf1em(flox)/Smoc 品系状...
To determine whether PU.1 is also required for the maintenance of MOZ-TIF2–induced AML, we infected fetal liver cells of PU.1 conditional knockout mice (Sfpi1flox/floxand expressing estrogen receptor (ER)-Cre) with MOZ-TIF2 and transplanted them into irradiated recipient mice, which develop...
from p48-CRE/LSL-KRas/p53 flox/flox mice (backcrossed C57/ B6, n ¼ 6 by speed congenic) by our laboratory. Kras-INK (KI) cells were obtained fromDr. Hanahan's laboratory (13, 14). All cell lines were negative for MAP and mycoplasma. Subsets of these cells were labeled with...