将IRES-iCre共表达结构插入到小鼠Csf1r基因终止密码子处。 应用领域:Cre工具鼠 *使用本品系发表的文献需注明: Csf1r-IRES-Cre mice (Cat. NO. NM-KI-190026) were purchased from Shanghai Model Organisms Center, Inc.. 验证数据 图1.流式检测Csf1r-Cre+/-;R26-mTmG+/-小鼠外周血巨噬细胞中荧光基因的...
To test the hypothesis, we created a hematopoietic calcium reporter mouse (Csf1r-Cre x GCaMP5) and non-destructively quantified the spatiotemporal dynamics of intracellular calcium in vitro and in vivo. In vitro, bone marrow derived macrophages calcium reporters reveal that fatal immune stimulatory ...
Cre~(ERT2) R26R~(EYFP)报告基因小鼠.此外,Csf1r-Cre~(ERT2)小鼠介导EYFP可有效标记小鼠组织CSF1R以及不同部位中CD45~+细胞.与R26R~(EYFP)组比较,Csf1r-Cre~(ERT2)小鼠介导EYFP标记效率最高的是脑组织(P<0.001),最低的是胸腺组织(P<0.05),脾脏组织则差异无统计学意义.结论 成年Csf1r-Cre~(ERT2)...
*使用本品系发表的文献需注明: hCSF1/hCSF1R(2) mice (Cat. NO. NM-HU-200273) were purchased from Shanghai Model Organisms Center, Inc.. 相关品系 Csf1r-IRES-Cre 品系名:C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc 品系状态:精子冻存 | 目录号:NM-KI-190026 hCSF1/hCSF1R(BALB/c) 品系名:BALB/...
Vil1-Cre mice and Csf1rFL/FL mice were used as transgenic controls. The numbers of lysozyme-expressing Paneth cells were unchanged in the intestinal crypts of Csf1rΔIEC mice compared to Vil1-Cre and Csf1rFL/FL transgenic control mice (Fig. 3g, h). Paneth cell morphology and expression ...
Fujii Y, Monteiro N, Sah S, Javaheri H, Ueki Y, Fan Z,et al. Tlr2/4-Mediated Hyperinflammation Promotes Cherubism-Like Jawbone Expansion in Sh3bp2 (P416R) Knockin Mice. JBMR Plus. 2022;6:e10562pubmedpublisher Almutairi F, Sarr D, Tucker S, Fantone K, Lee J, Rada B. RGS10 Re...
mice did not induce any measurable negative effects in animal behavior, including tests of anxiety (elevated plus maze; Fig.3g, h) and motor-function (open field; Supplementary Figure3A–D). Compared to wild-type animals, 5xFAD mice showed reduced anxiety-related behaviors compared to controls ...
from p48-CRE/LSL-KRas/p53 flox/flox mice (backcrossed C57/ B6, n ¼ 6 by speed congenic) by our laboratory. Kras-INK (KI) cells were obtained fromDr. Hanahan's laboratory (13, 14). All cell lines were negative for MAP and mycoplasma. Subsets of these cells were labeled with...
Methods:Using either Cx3cr1-iDTR mice in combination with Dtx or via the PLX5622 diet to pharmacologically ablate microglia, we compared the two models via MRI and histology to study the general anatomy of the brain and the CSF/ventricular systems. Additionally, we analyzed the cytokine profile...
To determine whether PU.1 is also required for the maintenance of MOZ-TIF2–induced AML, we infected fetal liver cells of PU.1 conditional knockout mice (Sfpi1flox/floxand expressing estrogen receptor (ER)-Cre) with MOZ-TIF2 and transplanted them into irradiated recipient mice, which develop...