Eight of the patients with the elevated CSF protein levels were male (62%) and one was female (9%). Depressed patients had significantly higher CSF protein levels (44.7 卤 18.0 mg/dl) than controls (31.5 卤 6.0 mg/dl) ( t = 3.32, df = 30.37, p = 0.002). No relationship was ...
Elevated levels of CSF total protein correlate to IL-8, MCP-1, and Loes MRI sev...Casal JA, Robles A, Tutor JC. Serum markers of mono- cyte/... JA Casal,A Robles,JC Tutor - 《Clinical Biochemistry》 被引量: 40发表: 2003年 Rapid mapping of interactions between Human SNX-BAR protei...
CSF Aβ42, Aβ40, neurofilament light (NfL), neurogranin, the soluble fragments of the triggering receptor expressed on myeloid cells 2 (sTREM2), Chitinase 3-like 1 (YKL40), glial fibrillary acidic protein (GFAP), S100 calcium-binding protein B (S100b), and α-synuclein (⍺-SYN) were...
c, d In older amyloid-negative, non-mutation carriers, total gray volume and production of APP are reduced relative to younger subjects. This decreases the flux toward Aβ peptides, including Aβ42. However, the ISF concentration of Aβ42 is only slightly elevated in younger subjects, ...
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31...
There is no doubt that these assay-level parameters enhance the technical measurement of a protein or molecule, but they alone are insufficient in rigor and reproducibility towards the measure's qualification as a biomarker. Unlike aqueous buffer solutions, human fluids contain large numbers of ...
to a cell, or nucleic acid, protein, or vector, indicates that the cell, nucleic acid, protein or vector, has been modified by the introduction of a heterologous nucleic acid or protein or the alteration of a native nucleic acid or protein, or that the cell is derived from a cell so ...
Elevated levels of CSF total protein correlate to IL-8, MCP-1, and Loes MRI severity score.Troy C., LundPaul, S. StademAngela, PanoskaltsisMortariGerald, RaymondWeston, P. MillerJakub, TolarPaul, J. Orchard
protein or molecule, but they alone are insufficient in rigor and reproducibility towards the measure’s qualification as a biomarker. Unlike aqueous buffer solutions, human fluids contain large numbers of biologically active substances which can influence any one biomarker’s structure, protein-binding,...
Surface molecules encoded by g2 genes are markedly elevated on mPMN-MDSCs from cancer patients and GDs. We then focused on g1 and g2 of the mPMN-MDSC gene signature (which both, different from g3, contain genes common to mNDNs and mLDNs from GDs) to examine whether they included gen...