PROTEIN-tyrosine kinasesTo identify markers in the CSF of multiple sclerosis (MS) subtypes, we used a two-step proteomic approach: (i) Discovery proteomics compared 169 pooled CSF from MS subtypes and inflammatory/degenerative CNS diseases (NMO spectrum and Alzheimer disease) and healthy controls....
CSF samples from 75 patients with RIS were analysed for chitinase-3-like protein 1, neurofilament light chain and oligoclonal bands.doi:10.1038/nrneurol.2018.26FyfeIanNat Rev NeurolNature Reviews Neurology
protein, were found in 62% ... D Riddoch,RA Thompson - 《Br Med J》 被引量: 58发表: 1970年 Intravenous Immunoglobulins in Multiple Sclerosis: Results of the Austrian Immunoglobulin in Multiple Sclerosis (AIMS) Trial Background: Multiple sclerosis (MS) is an autoimmune disorder characterized ...
Arnason. Multiple sclerosis: activated cells in cerebrospinal fluid in acute exacerbations. Ann.Neurol., 18:722–725 (1985). Article Google Scholar W. E. J. Weber, W.A. Buurman, Myelin basic protein-specific CD4+ cytolitic T-lymphocyte clones isolated from multiple sclerosis patients, Human...
CEREBROSPINAL FLUID (CSF) PROTEIN PATTERNS DETERMINED BY ISOELECTRIC FOCUSING IN MULTIPLE SCLEROSIS B.Perthen and W.Müller-Beißenhirtz Department of Clinical Chemistry,Bürgerhospital, D-7000 Stuttgart 1, F.R. of Germany Introduction Unique fractions or groups of fractions were demonstrated by isoe...
The present paper is concerned with a correlation between clinical parameters of multiple sclerosis (MS) and different agar gel electrophoresis patterns in cerebrospinal fluid (CSF). Agar gel electrophoresis clearly represents the most sensitive method f
(OND) patients, and 7 neurotic patients as controls were tested in an 125 I-labeled anti-human F(ab') 2 binding assay for the presence of antibodies to normal human brain cells from tissue culture, human fibroblasts, plasma membranes of MS and normal human brain, myelin basic protein (MBP...
Immunoblot detection of oligoclonal anti‐myelin basic protein IgG antibodies in cerebrospinal fluid in multiple sclerosis The CSF anti-MBP antibodies migrated to the anodal region of the IgG area in a different fashion from oligoclonal IgG and anti-measles IgG antibodies, ... M Cruz,T Olsson,J...
The two chemokines, monocyte chemoattractant protein (MCP)-1 and γ-interferon inducible protein (IP)-10, are thought to be involved in the pathogenesis of multiple sclerosis (MS). We measured MCP-1 and IP-10 levels in serum and CSF samples from 38 acute and 25 stable MS patients and fro...
:Rapid degradation restricts measles virus matrix protein expression in a subacute sclerosing panencephalitis cell line. Proc. Natl Acad Sci 83:7913–7917, 1986. CAS PubMed Google Scholar Vandvik B.:Oligoclonal IgG and free light chains in the cerebrospinal fluid of patients with multiple ...