Cryptococcus neoformans is endemic to the dry desert climates of California and Arizona. It can cause serious infections in animals and humans. Now comes a new species, C. gattii, which has been infecting animal
Disseminated infection with Cryptococcus neoformans var neoformans in an 8 years immunocompetent girl. Indian J Pediatr 2005;72:85.Wajid CM, Kabir S, Praveen K, Vivek D, Anan VK. Disseminated infection with Cryptococcus neoformans var neoformans in an 8 years immunocompetent girl. Ind J Pediat ...
Recurrent Meningeal Symptoms in Patients Treated For Cryptococcus neoformans Meningitis ( CnM ) and Starting HAARTSolomon, ChristinaMasliah, AlbertoMathews, W ChristopherMccutchan, J AllenStreet, West WashingtonDiego, San
Disease is often due to infection by the fungus Cryptococcus neoformans and involves a complex interaction between the human host and the fungal pathogen. Although previous studies have suggested genetic differences in the pathogen impact human disease, it has proven quite difficult to identify the ...
First Described: 1894, in a human patient in Germany (independently by Busse and Buschke). • Causes:Cryptococcus gattiispecies complex (SC),Cryptococcus neoformansSC, and rarely other cryptococcal species. The causative agents are basidiomycetes and usually referred to by their anamorph identification...
AlthoughC. neoformansis not typically considered a cytotoxic fungal pathogen, there is ample evidence to suggest that it can cause damage to host cells and tissues. Symptoms of infection withC. neoformanscomprise headache, fatigue, fever, and muscle aches, and in severe cases, the infection can ...
Virulence of Cryptococcus neoformans is regulated by a range of transcription factors, and is also influenced by the acquisition of adaptive mutations during infection. Beyond the temporal regulation of virulence factor production by transcription factor
CRYPTOCOCCUS neoformansEARLY diagnosisDIAGNOSIS methodsAMPHOTERICIN BA Cryptococcus subspecies, neoformans, represents the most pathogenic infection for humans, particularly in immunocompromised hosts (e.g., cancer patients, drug users). In the present study, we described a 67-year old woman with non-...
Cryptococcus neoformans is an encapsulated yeast-like fungus capable of causing life threatening meningoencephalitis in patients with impaired immunity. This microbe primarily infects the host via inhalation but has the ability to disseminate to the central nervous system (CNS) either as a single cell...
BackgroundPatients treated successfully for Cryptoccus neoformans meningitis (CnM) and initiating highly active antiretroviral therapy (HAART) may have recurrent CNS symptoms for a number of reasons including relapsing CnM or immune reconstitution inflammatory syndrome (IRIS). Anecdotal reports of CnM-...