neoformansCryptococcusgattiiVIRULENCERelatedFactorsBackground: Yeasts from the genus Cryptococcus (species C. neoformans and C. gattii ) are opportunistic pathogens that afflict humans with low immunity caused by diseases such as AIDS or by the usage of immunosuppressive drugs. It is a fatal disease ...
Cryptococcus neoformans is an opportunistic yeast responsible for lethal meningoencephalitis in humans. This pathogen elaborates a polysaccharide capsule, which is its major virulence factor. Mannose constitutes over one-half of the capsule mass and is also extensively utilized in cell wall synthesis and...
neoformans. The inhibition of C. neoformans growth was paralleled by production of nitrite, and reversed by the inhibitors of nitric oxide (NO.) synthase, NG-methyl-mono-arginine and NG-nitro-arginine methyl ester. The results suggest a novel function for human astrocytes in host defence and ...
Cryptococcus neoformans is a fungal pathogen of humans that causes life-threatening cryptococcal meningitis in immunocompromised patients, in particular those with advanced AIDS1. Cryptococcal meningitis is also found associated with a large variety of other immune deficient states, including in patients on...
C. neoformans is found in bird droppings and soil, and C. gattii is found in certain trees and soils. Humans become infected by inhaling airborne fungi into the lungs, where organisms can spread lymphohematogenously to the meninges. Clinical Manifestations. The most common presenting signs a...
Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans Hanhae Kim1*, Kwang-Woo Jung2*, Shinae Maeng2, Ying-Lien Chen3,4, Junha Shin1, Jung Eun Shim1, Sohyun Hwang1, Guilhem Janbon5, Taeyup Kim3, Joseph ...
Cryptococcus neoformansCryptococcosisRNA, FungalBody TemperatureGene Expression Regulation, FungalHost-Pathogen InteractionsStress, PhysiologicalRNA, MessengerCryptococcus neoformans is an environmental fungus that can cause severe disease in humans. C. neoformans encounters a multitude of stresses within the human...
Cryptococcus neoformans is an important opportunistic fungal pathogen in humans. Recent studies have demonstrated that metals are critical factors for the regulation of fungal virulence in hosts. In this study, we systemically investigated the function of C. neoformans magnesium transporters in controlling...
Secreted phospholipase B (PLB1), which contains three enzyme activities in the one protein, is necessary for the initiation of pulmonary infection by Cryptococcus neoformans and for dissemination from the lung via the lymphatics and blood. Adhesion to lung epithelium is the first step in this pro...
(Biology) any fungus of the genusCryptococcus, some of which cause disease in animals and humans Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 ...