[7] T.A. M. Bharat, C. J. Russo, J. Lowe, L. A. Passmore, S. H. W. Scheres, Advancesin Single-Particle Electron Cryomicroscopy Structure Determination applied toSub-tomogram Averaging. Structure 23, 1743-1753 (2015).[8] B.A. Himes, P. Zhang, emClarity: software for high-resolu...
Cryo-EM structure of the DNA-PK holoenzyme. Proc Natl Acad Sci USA 2017; 114:7367–7372. Article CAS Google Scholar Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O . Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB...
CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution Article Open access 13 May 2021 Introduction The type IIA DNA topoisomerases (Top2) are nanomachines that control DNA topology during multiple cellular processes such as replication, transcription and cell division1,2,3...
The cryoEM structure of 44m Fab in complex with fully-cleaved glycosylated native-like BG505.SOSIP envelope trimer at 4.4 resolution revealed that 44m ... S Kumar,S Singh,A Chatterjee,... - 《Biorxiv》 被引量: 0发表: 2023年 Structure-guided envelope trimer design in HIV-1 vaccine deve...
We have solved the cryo-EM structure of the cytoplasmic ribosome from the human malaria parasite, Plasmodium falciparum, in complex with emetine at 3.2 ?? resolution. Emetine is an anti-protozoan drug used in the treatment of ameobiasis that also displays potent anti-malarial activity. Emetine ...
Figure 2. Cryo-EM Structure of T. maritima Mg2+ Channel CorA in the Presence of Mg2+ at 3.8-Å Resolution (A) Side view of density map and fitted coordinates in ribbon representation of the entire pentamer with each protomer shown in a different color (A, orange; B, magenta; C, bl...
Fig. 1. Cryo-EM structure of the MeV N core -RNA nucleo- capsid at near-atomic reso- lution. (A) Schematic of MeV N (navy blue, NTD arm; blue, NTD; salmon, CTD; yellow, CTD arm). The same color code (with RNA in green) is ...
Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature 546, 248–253 (2017). Article ADS PubMed PubMed Central CAS Google Scholar Liang, Y. L. et al. Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature 546, 118–123 (2017)....
Cryo-EM structure of human mTOR complex 2 Structural and MS analyses reveal the presence of inositol hexaphosphate (InsP6) in the SMG1 kinase. We show that the InsP6-binding site is conserved in mammalian target of rapamycin (mTOR) and potentially other PIKK members, and ... X Chen,M Li...
Johnson - 《Structure》 被引量: 8发表: 2012年 Reconstructing Cyano-bacteriophage P-SSP7 structure without imposing symmetry The 9 structure of P-SSP7 was determined by single particle cryo-electron microscopy (cryo-EM) reconstruction without imposing any symmetry. The icosahedral features of the ...