Dietary intake of phytate has various reported health benefits. Previous work showed that the gut microbiota can convert phytate to short-chain fatty acids (SCFAs), but the microbial species and metabolic pathway are unclear. Here we identified Mitsuokel
肠道微生物之间“相互喂食”(cross-feeding)可以帮助它们对抗宿主饮食的变化》。 现在把文章中一些比较有意思的内容摘抄出来分享给各位朋友。 (1)While in specific cases single microbes can be identified as the sole drivers affecting the host2...
jalaludinii, are prevalent in human gut microbiomes. NMR spectroscopy using13C-isotope labelling, metabolomic and transcriptomic analyses identified a complete phytate degradation pathway inM. jalaludinii, including production of the intermediate Ins(2)P/myo-inositol. The major end product, 3-...
Together, our results demonstrate that obligate cross-feeding can significantly expand the ecological niche space of interacting bacterial genotypes, thus explaining the widespread occurrence of this type of ecological interaction in natural microbiomes. This is a preview of subscription content, access ...
We found that ILA is a key molecule of Lactobacillus in the alleviation of inflammation and modulation of the gut microbiota. ILA increased the expression of relevant enzymes involved tryptophan metabolism via bacterial cross-feeding and promoted the synthesis of microbial tryptophan metabolites including...
Together, our results demonstrate that obligate cross-feeding can significantly expand the ecological niche space of interacting bacterial genotypes, thus explaining the widespread occurrence of this type of ecological interaction in natural microbiomes. 展开 ...
(Fig.1). UC is a subtype of inflammatory bowel disease (IBD), a chronic inflammatory condition of the gastrointestinal tract that has been associated with dramatic changes in the gut microbiome [5,71]. As input, we used species-level taxonomic profiles available through thecuratedMetagenomicsData...
As my kids have begun to go to school, feeding them things to improve their immune system has been a topic of focus in my house. Here’s why….Nearly 70% of the immune system resides in the gut. 70%! That’s as much of the Earth’s surface covered in water! A diverse and thriv...
Microbes frequently rely on metabolites excreted by other bacterial species, but little is known about how this cross-feeding influences the effect of antibiotics. We hypothesized that when species rely on each other for essential metabolites, the minimu
Metabolic specificity exists between different bifidobacteria and other gut microbiota in the range, species, and utilization strategies of available glycans, which induces interactions between bifidobacteria and other flora, including cross-feeding, to promote the gut adaptability of bifidobacteria28. The ...