Cross-couplingLigandsCatalysisIndolylphosphines have been successful as unique and efficient ligands for palladium-catalyzed cross-coupling reactions. This review summarizes the recent decade developments and applications of different coupling partners in these reactions that employ indolylphosphines as ...
et al. Alkyl sulfinates as cross-coupling partners for programmable and stereospecific installation of C(sp3) bioisosteres. Nat. Chem. 15, 550–559 (2023). https://doi.org/10.1038/s41557-023-01150-z Download citation Received15 September 2021 Accepted30 January 2023 Published02 March 2023 ...
1f, see key intermediate), which was pioneered by Martin group several decades ago37,38,39, could potentially be utilized to activate the C–S bond, facilitating alkyl aryl sulfoxides as electrophilic coupling partners in the subsequent transition-metal-free coupling reactions with alcohols. This ...
CuTc and Et2O turned out to be the optimal catalyst and solvent. This reaction featured with very broad substrate scope. A wide range of terminal alkynes including aryl alkynes, heteroaryl alkynes,silylalkyne, and alkyl alkynes were suitable for cross-coupling partners. Impressively, bothpropyneand...
also applied to the synthesis of a series ofmeta-phosphonate-substituted arylboronic esters via a sterically-controlled regioselective C-H borylation of the corresponding 3-substituted aryl phosphonates; the resulting boronate esters were then used as nucleophilic coupling partners in a subsequent ...
The disadvantages of using aryl triates as electrophilic coupling partners have already been discussed in Section 3.1. Ar1OTf + Ar2BF3K 5 mol% Pd(OAc)2 10 mol% PCy3 3 equiv Cs2CO3 THF-H2O 10:1 reflux, 20 h of Leadbeater also coupled successfully several organotriuoroborates with ...
Allenyl ketones are employed as coupling partners in palladium-catalyzed oxidative cross-coupling reactions with organoboronic acids. This reaction constitutes an efficient methodology for the synthesis of highly substituted furan derivatives. Palladium-carbene migratory insertion is proposed as the key step...
cross-couplingindiumpalladiumInter- and intramolecular palladium-catalyzed allyl cross-coupling reactions, using allylindium generated in situ from allyl halides and indium, is demonstrated. Allylindium compounds may be effective nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions. A...
transmetalation of π-allylpalladium(II) complexes, obtained from allyl acetates and palladium(0) catalyst, with indium and indium(III) chloride are effective nucleophilic cross-coupling partners in Pd-catalyzed allyl cross-coupling reactions with a variety of electrophilic cross-coupling partners.关键...
A reasonably efficient Pd-catalyzed cross-coupling of diazine N -oxides with arylhalides to afford aryl diazines is reported. In view of the absence of metalated (B, Zn, Mg, Sn) partners, the process may be formally categorized in the C-H-activation group of reactions. The reaction proceeds...