[8] TORRES-RUIZ R, RODRIGUEZ-PERALES S. CRISPR-Cas9 technology: applications and human disease modelling[J/OL]. Briefings in Functional Genomics, 2017, 16(1): 4-12. DOI:10.1093/bfgp/elw025. [9] CHEN M, MAO A, XU M, 等. CRISPR-Cas9 for cancer therapy: Opportunities and challenges[...
CRISPR-Cas technology in corn: a new key to unlock genetic knowledge and create novel productsCRISPR-CasMaizeGenome editingSince its inception in 2012, CRISPR-Cas technologies have taken the life science community by storm. Maize genetics research is no exception. Investigators around the world have...
[6] Fang L, Yang L, Han M, Xu H, Ding W, Dong X. CRISPR-cas technology: A key approach for SARS-CoV-2 detection. Front Bioeng Biotechnol. 2023 Apr 12;11:1158672. doi: 10.3389/fbioe.2023.1158672.
再后来,人们陆续发现了CRISPR/Cas9作用的完整的分子生物学机制,从而发现并挖掘了它改造为基因编辑工具的巨大潜力。 延伸阅读:History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology,这篇文章的作者之一是CRISPR的发现者之一石野良纯。本表根据该文及鲁道夫·巴兰戈与约...
华中农业大学农业微生物国家重点实验室李英俊团队近期在Engineering Microbiology杂志上发表了题为“CRISPR-based gene editing technology and its application in microbial engineering”的综述论文,系统梳理了不同CRISPR-Cas系统的原理以及其在微...
2013年初的《科学》第339卷第6121期连载了两篇具有重要意义的CRISPR技术论文,其中一篇描述的是麻省理工学院(Massachusetts Institute of Technology, MIT)Zhang的研究组使用CRISPR技术完成了多重基因组编辑,另一篇描述了哈佛医学院(Harvard Medical School)Church的研究组首次使用CRISPR技术完成了RNA介导的人类基因组编辑(图...
[4] Ishino Y, Krupovic M, Forterre P. History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology. J Bacteriol. 2018 Mar 12;200(7):e00580-17. doi: 10.1128/JB.00580-17. PMID: 29358495; PMCID: PMC5847661. ...
The emergence of the gene editing technology, especial CRISPR-Cas (clustered regularly intersected short palindromic repeats and CRISPR associated proteins), has greatly promoted the ability of human beings to transform natural species. It has been widely harnessed for the engineering in the medical, ...
Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by many biological researchers. This widespread adoption has been largely fueled by the emergence of the clustered, regularly interspaced, short palindromic repeat (CRISPR) ...
Kotagama, O.W. et al. Era of genomic medicine: a narrative review on CRISPR technology as a potential therapeutic tool for human diseases. Biomed Research International, 2019 (2019). doi: 10.1155/2019/1369682. Ran FA, et al. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome edi...