参考资料: [1] Yang and Doudna, (2023). CRISPR technology: A decade of genome editing is only the beginning. Science, https://doi.org/10.1126/science.add8643 ▎药明康德内容团队编辑 本文来自药明康德内容团队,欢迎转发,谢绝转载到其他平台。 免责声明:药明康德内容团队专注介绍全球生物医药健康研究进展。...
The following three types of genetic engineering technologies are used to generate genetically engineered mouse(GEM) models: Embryonic stem cell targeting technology CRISPR gene editing technology Transgenic technology Comparison Embryonic Stem Cell Targeting In murine embryonic stem cells, the exchange of an...
摘要:CRISPR/Cas系统是近年来被广泛应用于基因组编辑的一项新兴技术,其中CRISPR/Cas12a技术由于具有独特的优势,受到越来越多的关注 基因组编辑(genomeediting)是对细胞内的目标遗传物质进行特定改造的一种技术,包括DNA删除、替换、插入、易位、点突变等。基因组编辑技术在分子生物学领域发挥着重要作用,通过对目的基因进行...
摘要:CRISPR/Cas系统是近年来被广泛应用于基因组编辑的一项新兴技术,其中CRISPR/Cas12a技术由于具有独特的优势,受到越来越多的关注 基因组编辑(genomeediting)是对细胞内的目标遗传物质进行特定改造的一种技术,包括DNA删除、替换、插入、易位、点突变等。基因组编辑技术在分子生物学领域发挥着重要作用,通过对目的基因进行...
[1] Yang and Doudna, (2023). CRISPR technology: A decade of genome editing is only the beginning. Science, https://doi.org/10.1126/science.add8643 本文来自药明康德内容团队,欢迎个人转发至朋友圈,谢绝媒体或机构未经授权以任何形式转载至其他平台。转载授权请在「药明康德」微信公众号留言联系我们。其他合...
Repurposed CRISPR/Cas9 is an emerging technology focusing on engineering genetic devices and circuits for a variety of applications from biotechnology to medicine. Scientists are now able to construct Cas9-based gene circuits for cancer intervention, thus providing robust therapeutic strategies for cancer...
Dimitri A, Herbst F, Fraietta JA. Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing. Mol Cancer. 2022;21(1):78. Huang S, Yan Y, Su F, et al. Research progress in gene editing technology. Front Biosci (Landmark Ed). 2021;26(10):916-927. ...
Xin-ru, CHEN Mao-sen, ZHONG Jie, QI Feng. Characteristics and Application of CRISPR/Cas12a Genome Editing Technology. Journal of Chinese Biotechnology, 2023, 43(10): 32-42 doi:10.13523/j.cb.2304020 转载说明:本文图文源自Journal of Chinese Biotechnology,仅做学术分享使用;感谢每一位作者的辛苦付出...
2023年1月20日,美国加州大学伯克利分校Jennifer A. Doudna在Science在线发表题为“CRISPR technology: A decade of genome editing is only the beginning”的综述论文,该综述讨论了CRISPR介导的基因操纵在人类细胞、动物和植物中的现状,以及...
[1] Wang J Y, Doudna J A. CRISPR technology: A decade of genome editing is only the beginning[J]. Science, 2023, 379(6629): eadd8643. [2] Y. Ishino, H. Shinagawa, K. Makino, M. Amemura, A. Nakata,Nucleotide sequence of the iap ...