Spatiotemporal gene control by the Cre-ERT2 system in melanocytes. Genesis 44, 34-43 (2006).Yajima I, Belloir E, Bourgeois Y et al. (2006) Spatiotemporal gene control by the Cre-ERT2 system in melanocytes. Genesis 44:34-43Yajima I, Belloir E, Bourgeois Y, Kumasaka M, Delmas V, ...
Cre-ERT2小鼠是一类含有雌激素受体(estrogen receptor,ER)的配体结合区突变体(ERT)与Cre重组酶的融合蛋白表达的小鼠。Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。 Tamoxifen给药建议如下:...
Microglia are macrophages resident in the central nervous system. C-X3-C motif chemokine receptor 1 (CX3CR1) is a Gαi-coupled seven-transmembrane protein exclusively expressed in the mononuclear phagocyte system including microglia, as well as intestina
造血干祖细胞体外定向诱导分化为粒细胞的研究 星级: 4页 小鼠肿瘤坏死因子α增强造血干祖细胞归巢效率的机制研究 星级: 6页 三氧化二砷对小鼠骨髓基质细胞和造血干祖细胞影响的实验研究论文 星级: 48 页 当归多糖动员的造血干祖细胞移植重建小鼠造血功能的研究 星级: 4页 胚胎干细胞向造血干祖细胞定向诱导分化的研...
13:88 https://doi.org/10.1186/s13041-020-00630-4 MICRO REPORT Open Access Cx3cr1CreERT2-driven Atg7 deletion in adult mice induces intestinal adhesion Younghwan Lee1, Ji-Won Lee1, Hyeri Nam1 and Seong-Woon Yu1,2* Abstract Microglia are macrophages resident in the central nervous system...
The Mds1CreERT2 model will be useful to address multiple questions regarding the complexity of the hematopoietic system as it unfolds in the murine embryo and continues to function postnatally. Results Embryonic expression of Mecom We reported previously the expression pattern of Mecom transcripts ...
Microglia are macrophages resident in the central nervous system. C-X3-C motif chemokine receptor 1 (CX3CR1) is a Gαi-coupled seven-transmembrane protein exclusively expressed in the mononuclear phagocyte system including microglia, as well as intestina
C-X3-C motif chemokine receptor 1 (CX3CR1) is a Gαi-coupled seven-transmembrane protein exclusively expressed in the mononuclear phagocyte system including microglia, as well as intestinal and kidney macrophages. Cx3cr1CreERT2 mice express Cre recombinase in a tamoxifen-inducible manner and ...
基金 安徽省教育厅高校科学研究项目(编号:2022AH020052)。 关键词 Csf1r-CreERT2 R26REYFP CRE/LOXP系统 CD45 流式细胞术 Csf1r-CreERT2 R26REYFP Cre/LoxP system CD45 flow 分类号 R394.2 [医药卫生—医学遗传学] 登录即可查看详情 安徽医科大学学报 2024年 第7期 职称评审材料打包下载 ;...
NG2 (nerve/glia antigen-2) is a type I transmembrane glycoprotein and also known as chondroitin sulfate proteoglycan 4. In the parenchyma of the central nervous system, NG2-expressing (NG2+) cells have been identified as a novel type of glia with a strong potential to generate oligodendrocyte...