In this study, we introduced CRlncRC, a novel Cancer-Related lncRNA Classifier by integrating manifold features with five machine-learning techniques.doi:10.1186/s12920-018-0436-9Zhang, XuanWang, JunLi, JingChen, WenLiu, ChangningBioMed CentralBMC Medical Genomics...
In addition, Gli1 could also be enhanced by β-catenin though c-myc, which binds to the coding region of Gli1 mRNA to increase stability [166]. Furthermore, a previous study indicated that SMO can inhibit the activity and nuclear translocation of β-catenin, which does not rely on the ...
Kermanshah University of Medical Sciences, Kermanshah, Iran Abstract Background: It seems that several members of intestinal gut microbiota like Strepto- coccus bovis, Bacteroides fragilis, Helicobacter pylori, Fusobacterium nucleatum, Enterococ- cus faecalis, Escherichia coli, Peptostreptococcus ...
The coding sequences of full-length human BRCA1 tagged with 3 × Flag at the N-terminus, mCherry and ubiquitin (wild-type, K48-, K63-, K6-, K11- or K27-specifity) tagged with HA at the N-terminus were inserted into the pCDH-EF1-MCS-T2A-Puro plasmid respectively. ShRNAs targeting...
Project collateral and source code discussed in this application report can be downloaded from the following URL: http://www.ti.com/lit/zip/spna235. NOTE: TI assumes no liability that the discussed implementation and provided code are free from faults, compliant to certain coding guidelines, ...
Long noncoding RNAs (lncRNAs) are pervasive transcripts that play pivotal roles in regulating chromatin dynamics, gene and protein expression. Aberrant expression and mutations of lncRNAs represent a driving force behind tumor invasion and metastasis, ma
Chromosomal instability (CIN) is involved in about 70% of colorectal cancers (CRCs) and is associated with poor prognosis and drug resistance. From a clinical perspective, a better knowledge of these tumour’s biology will help to guide therapeutic strat
This work was supported by Beijing medical health charity foundation (supported by the medical research foundation) Project number YWJKJJHKYJJ-B17775 and Major Projects of in-hospital Fostering Fund of Affiliated Hospital of Yan’an University in 2018(Grant No. 2018ZDA-03). Appendix A. Supplementa...
Doctor–patient communication was explored using RIAS coding which is a method widely used for coding medical dialogue [7]. Forty codes defined in the RIAS handbook were used to distinguish task-related and socioemotional communication. Task-related codes include medical condition, therapeutic regimen,...
(miR) are 20-to-24 nucleotides small noncoding RNAs, generated by Dicer processed ~ 70-base single-stranded RNA precursor [2,3,4], exert epigenetic regulation at transcription level by recognizing homologous mRNA sequence, which have been a research hotspot since first discovery in 1993 [...