BACKGROUND Craniosynostosis is a condition in which 2 or more of the skull bones fuse prematurely. The spectrum of the disorder most commonly involves the closure of a single suture in the skull, but it can also involve syndromic diagnoses in which multiple skull bones and/or bones outside ...
Hydrocephalus: A condition in which there is impaired blood flow or impaired absorption of the fluid circulating through the ventricles of the brain and spinal canal leading to increased fluid on the skull, affecting up to 30% of people with Crouzon syndrome6 Acanthosis nigricans: A skin condition...
It is usually best for your baby to have the surgery before they reach age 1. This is because the bones are still very soft. It is easier to fix the deformities at that time. Your baby may need surgery at a much earlier age if the condition is more serious. Most surgeries are done ...
when this suture is patent, followed by a sharp decrease in CD51+;CD200+cells starting at pN7 (Fig.1b). pN7 is prior to the onset of chondrogenesis which precedes suture closure (Fig.1c)10. By pN17, when the PF suture is fused10, CD51+;CD200+cells represented only...
Craniosynostosis affects approximately one in every 2,500 babies in the United States. The condition is caused by the premature closure of sutures with bone. Sutures, which are made of tissue that is more flexible than bone, play an important role inbrain growthby providing a method for the ...
Early fusion of the sagittal suture is a clinical condition called, sagittal craniosynostosis. Calvarial reconstruction is the most common treatment option for this condition with a range of techniques being developed by different groups. Computer simulations have a huge potential to predict the calvarial...
Craniosynostosis is a common birth defect, appearing in ∼1 of 2500 live births (1, 2). This condition is characterized by premature fusion of one or more cranial sutures, which causes abnormal skull shapes and cognitive disabilities if surgical reconstructions are not performed (1, 2). Consid...
Sagittal craniosynostosis, a condition in which the cranial bones fuse too early, affects around one in every 5000 newborn babies. Using 130 European families (affected child plus both parents), Justice et al. carried out a genome-wide association study (GWAS) for the nonsyndromic form of the...
Nonsyndromic craniosynostosis is a common condition resulting from premature fusion of one or more cranial sutures, in the absence of a particular syndrome. Nonsyndromic craniosynostosis results in a predictable head shape dictated by which suture(s) is fused. Craniosynostosis is traditionally treated ...
In recent years, there has been an apparent increase in the incidence of posterior plagiocephaly following changes in the sleeping habits of infants as a result of the recommendation of the American Task Force on Infant Position and Sudden Infant Death Syndrome, which has favored a supine ...