While motor and cognitive development in the first years of life may be in line with expectations, later performance on developmental tests may be lower than expected [31]. Magge et al. described that 50% of children with ISS between the ages of 6 and 16 had learning and reading ...
mesenchymal stem/progenitor cells toward the osteogenic lineage via the retinoic acid (RA) pathway [22]. As RA acts as a morphogen and is reported to have a role in bone development, precise control of ERF nuclear levels and transcriptional effects appear to be important for multiple cellular ...