CpG ODN, type B (human) - TLR9-based vaccine adjuvant TLR9 activation with ODN 2006 InvivoGen also offers: •TLR reporter cells:HEK293, RAW, THP-1 cells •TLR research tools:Antibodies, Inhibitors, etc. ODN 2006 VacciGrade™ (ODN 7909) is a Class B CpG oligonucleotide (ODN) with...
CpG 2006 ODN (also known as CpG ODN 7909) is a human TLR9 ligand. InvivoGen's CpG oligonucleotides are functionally tested and guaranteed endotoxin-free to avoid non-specific immune stimulation. The sequence of CpG-B (type K) ODN 2006 (also known as PF-3
用不同浓度的B-class CpG ODNs, ODN 1668, ODN 1826, ODN 2006 或 ODN 2007及相应的对照ODNs 刺激HEK-Blue™ hTLR9 细胞 (表达人源TLR9和NF-κB诱导 SEAP 报告基因, 刺激物与HEK-Blue Detection试剂共孵育24 小时, NF-ΚB-诱导 SEAP的水平在OD 655 nm检测。 Class B CpG ODNs 刺激 HEK-Blue™ ...
The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro Article Open access 15 July 2020 A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategies Article Open access 05...
The adjuvant activity of synthetic TLR9 ligands was evaluated in various human clinical trials includ- ing malaria (13,30), influenza (31) and hepatitis B. In case of hepatitis B, the vaccine Engerix-B coadministered with CpG ODN significantly improved the antibody response in healthy individuals...
CpG-ODN:Themodulatorofimmuneresponse ZHENGJian.feng (UnionHospital,TorsiMedicalCollege,HuazhongUniversityofScienceandTechnology, Wuhan430022, China) AbstractToll-likereceptors(TLR)aleprimarilythoughttoplayanimportantroleinrecogniti onofpatho- genandactivationofinnateimmuneresponse,andnOWitisfoundthattheinteractionbet...
Interestingly, the combined CD1d immunotherapy and peptide/CpG-ODN immunization resulted in a synergistic effect on the expansion of NK cells with a threefold in- creased frequency at day 7 in the spleen (Figure 2B, right), while peptide/CpG-ODN vaccine alone had no effect on NK cells. The...
2. 诱导原代人CLL细胞极化和迁移,ODN 2395/ODN 2006 ODN 2088 —TLR 9拮抗剂 通过破坏CpGODNs与TLR9在内涵体囊泡中的共区域化而发挥作用,而不影响细胞结合和摄取。 应用: 1. TLR9抑制剂治疗大鼠疾病模型,ODN 2088 CpG ODN的选择你明白了吗? InvivoGen 1977年成立于法国,是法国第一家生物科技公司。公司成立...
TLR9 activation with ODN 2006 InvivoGen provides ODN 2006, a Class B CpG oligonucleotide (ODN) witha preference for the human Toll-like receptor 9 (TLR9).Class B (Type K) CpG ODNs, such as ODN 2006, contain a full phosphorothioate backbone with one or more CpG dinucleotides. ...
CpG 2006 Biotin ODN (also known as CpG ODN 7909 Biotin) is a labeled human TLR9 ligand. InvivoGen CpG oligonucleotides are functionally tested and guaranteed endotoxin-free to avoid non-specific immune stimulation. The sequence of CpG-B (type K) ODN 2006