Conclusion Investigation of ex-vivo CRC cells by flow cytometry demonstrated COX-2 expression rates comparable to that previously reported. However, expression by paired live normal colon was significantly greater, suggesting that COX-2 may be expressed at higher rates in normal colonic cells in ...
COX-2 expression in normal and neoplastic breast tissue. For each tissue, the thick black horizontal bars represent the median COX-2 score, the boxes represent the interquartile range and the T-bars the full range. The median COX-2 expression in neoplastic DCIS and invasive cancer epithelium a...
[4]马家驰,赵晓丹,亓建波,等.前列腺素E2和环氧化酶2在结直肠癌组织中的表达及其临床意义[J].中华普通外科杂志,2018,33(04):322-325. [5]Kosumi K, Hamada T, Zhang S, et al.Prognostic association of PTGS2 (COX-2) over-expression according to BRA...
3.3. Cox-2 expression in canine melanocytic tumours The expression of COX-2 was absent in 18/37 (48,6%) of the canine melanocytic tumours (Fig. 4). None of the 8 benign tumours expressed Cox-2 in tumoural cells. ...
Thus, Sp1 could transcriptionally activate COX-2 expression in a process relies on activated EGFR/p38-MAPK signaling. Finally, we found that the inhibition of COX-2 leads to decreased angiogenesis in a process dependent on VEGF, which link COX-2 to angiogenesis in PDAC....
COX2 EXPRESSION IN EL-POSITIVE CELLS INDUCES ABERRANT DUCT DEVELOPMENTacute pancreatitiscourse predictionacute phaseObjectives: Of patients with acute pancreatitis (AP), 20% develop severe attacks that need early and intensive therapy. Yet, to administer such treatment, it is important to classi...
These data show that increased COX2 expression alone can enhance the tumorigenic properties of neuroblastoma cells; however, high levels of COX2 may not be a valid biomarker of sensitivity to non-steroidal anti-inflammatory drugs such as celecoxib. 展开 ...
宫颈癌组织中sox-17和cox-2的表达及意义-expression and significance of sox - 17 and cox - 2 in cervical cancer tissues 中英文缩略词一览表英文缩写SOX-17英文全称SRY-boxcontaininggene17中文全称SRY盒包含基因-17SRYCOX-2CINSPsexdeterminingregionYcyclooxygenase-2cervicalintraepithelialneoplasiaStreptavidin-pero...
Conclusions Transcription and external cell signaling factors are altered as covariates to COX-2 expression in colon cancer tissue, but DNA methylation of the COX-2 promoter region was not a significant factor behind COX-2 expression in tumor and normal colon tissue.Peer...
The expression level of Cox-2 mRNA in breast tumor tissue was significantly upregulated(with a range of 0.03-0.99) compared with that in both paired adjacent breast tissues(with a range of 0.01-0.52) and paired normal breast tissues(nearly no expression),P0.05.The expression of Cox-2 was ...