Gene Expression RegulationNeoplastic乳腺肿瘤癌导管内非浸润性Cyclooxygenase type-2 (COX-2) is overexpressed in malignant tumours including breast cancers, though the mechanism of upregulation is unclear. This study aimed to determine COX-2 expression in ductal carcinoma in situ (DCIS) in comparison to...
COX2 expression is elevated in cancers and adenomas compared with normal bowel tissue, and experimental evidence suggests that inhibition of COX2 (through the use of agents such as nonsteroidal anti-inflammatory drugs) suppresses development of adenoma and colorectal cancer. The results of previous ...
classified as COX-2 negative), (B) moderate COX-2 staining with approximately 5060% of cells strongly stained (score 2+, classified as COX-2 positive), (C) High COX-2 expression in cribriform DCIS with 100% of cells intensely stained (score 3+, classified as COX-2 positive)...
[5]Kosumi K, Hamada T, Zhang S, et al.Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial. Eur J Cancer. 2019 Apr...
COX2 EXPRESSION IN EL-POSITIVE CELLS INDUCES ABERRANT DUCT DEVELOPMENTacute pancreatitiscourse predictionacute phaseObjectives: Of patients with acute pancreatitis (AP), 20% develop severe attacks that need early and intensive therapy. Yet, to administer such treatment, it is important to classi...
3.3. Cox-2 expression in canine melanocytic tumours The expression of COX-2 was absent in 18/37 (48,6%) of the canine melanocytic tumours (Fig. 4). None of the 8 benign tumours expressed Cox-2 in tumoural cells. ...
Increased cyclooxygenase activity promotes progression of colorectal cancer, but the mechanisms behind COX-2 induction remain elusive. This study was therefore aimed to define external cell signaling and transcription factors relating to high COX-2 expression in colon cancer tissue. Method Tumor and norma...
The expression level of Cox-2 mRNA in breast tumor tissue was significantly upregulated(with a range of 0.03-0.99) compared with that in both paired adjacent breast tissues(with a range of 0.01-0.52) and paired normal breast tissues(nearly no expression),P0.05.The expression of Cox-2 was ...
Objective It is to investigate the expression of COX- 2 and IL- 17 in the oral lichen planus and oral squamous cell carcinoma,and analyze their relationships and clinical significance. Methods The expression of Cox- 2 and IL- 17 of 20 cases of oral lichen planus( lichen planus group),20 ...
宫颈癌组织中sox-17和cox-2的表达及意义-expression and significance of sox - 17 and cox - 2 in cervical cancer tissues 中英文缩略词一览表英文缩写SOX-17英文全称SRY-boxcontaininggene17中文全称SRY盒包含基因-17SRYCOX-2CINSPsexdeterminingregionYcyclooxygenase-2cervicalintraepithelialneoplasiaStreptavidin-pero...