伐地考昔是一种高效和选择性的COX-2抑制剂,对COX-2和COX-1的IC50分别为5nM和140μM。伐地考昔可用于关节炎和疼痛的研究。 图1.(Valdecoxib)代他考昔分子结构 (Valdecoxib)代他考昔基础信息 中文名:代他考昔;COX-2选择性抑制剂 英文名:Valdecoxib;COX-2 selective inhibitor 分子式:C16H14N2O3S 分子...
中文名：代他考昔；COX-2选择性抑制剂 英文名：Valdecoxib；COX-2 selective inhibitor 分子式：C16H14N2O3S 分子量：314 结构式：CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N 熔点：162-164℃ 沸点：481.2±55.0 °C at 760 mmHg 闪点：244.8±31.5 °C 密度：1.3±0.1 g...
伐地考昔是一种高效和选择性的COX-2抑制剂,对COX-2和COX-1的IC50分别为5nM和140μM。伐地考昔可用于关节炎和疼痛的研究。 图1.(Valdecoxib)代他考昔分子结构 (Valdecoxib)代他考昔基础信息 中文名:代他考昔;COX-2选择性抑制剂 英文名:Valdecoxib;COX-2 selective inhibitor 分子式:C16H14N2O3S 分子...
Cox-2 inhibitor (redirected fromCOX-2 selective inhibition) Thesaurus Medical Encyclopedia n. Any of a class of nonsteroidal anti-inflammatory drugs that selectively block prostaglandin formation so as to cause minimal gastrointestinal side effects. ...
While lacking some of the troublesome adverse effects of opioids, non-selective NSAIDs may cause bleeding, gastric ulceration, and renal injury as a result of their inhibitory effects on cyclo-oxygenase–1 (COX–1). Cyclo-oxygenase–2 (COX–2) is normally present in small concentrations, but...
Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis ObjectivesTo investigate the cost effectiveness of cyclo-oxygenase-2 (COX 2) selective inhibitors and traditional non-steroidal anti-inflammatory ...
The inhibitory effect of the former against COX-2 is significantly stronger than that against COX-1, but also partially inhibits COX-1 at the same time, while the latter only has strong inhibitory effect on COX-2 inhibitor. The main adverse reactions of selective COX-2 inhibitors are ...
1.The study about the inhibitive effect ofselective COX-2 inhibitoron periprosthetic capsule formation in rabbits选择性COX-2抑制剂减少硅凝胶假体置入后包膜形成的实验研究 2.Objective To study long-term learning and memory capacity effects on the neonatal hypoxic-ischemic brain damage(HIBD) rats after ...
Angiogenesis and Tumor Progression Inhibition of Cyclooxygenase-2 Selective Inhibitor Celecoxib Associated with Poly (lactic-co-glycolic acid) in Tumor Cell Line Resistant to Chemotherapy/Inhibicion de Angiogenesis y Progresion Tumoral por Inhibidor Selectivo de Ciclooxigenasa-2 Celecoxib Asociado con Acido...