The enzymes that convert arachidonic acid to prostaglandin H2 are named cyclooxygenase-1 (COX-1) and COX-2. The properties of COX-1 are different from those of COX-2. It was originally thought that the function of COX-1 was involved in physiological phenomena, whereas that of COX-2 was ...
[-hzh-] 一度认为COX-1不直接参与炎症,然而近期研究发现,在类风湿关节炎患者的滑膜组织可测出COX-1和COX-2,在体外培养的类风湿滑膜细胞显示巨噬、纤维母、内皮及单个核炎性细胞均表达二种酶[1]。敲出COX-1的鼠可减轻对花生四烯酸的炎症反应,而敲出COX-2的鼠经炎性刺激同样可出现炎症反应,且其反应程度与...
Distinct functions of COX-1 and COX-2. The enzymes that convert arachidonic acid to prostaglandin H2 are named cyclooxygenase-1 (COX-1) and COX-2. The properties of COX-1 are different from thos... Morita,Ikuo - 《Prostaglandins》 被引量: 472发表: 2002年 Comparative analysis of pharmacolog...
Define cox. cox synonyms, cox pronunciation, cox translation, English dictionary definition of cox. n. A coxswain. intr. & tr.v. coxed , cox·ing , cox·es To act as coxswain or serve as coxswain for. American Heritage® Dictionary of the English Langu
Perspective assessment of COX-1 and COX-2 selectivity of nonsteroidal anti-inflammatory drugs from clinical practice: use of genetic function approximation. The beneficial action of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with the inhibition of cyclooxygenase-2 (COX-2), whereas th...
Cox-1 and Cox-2 expression in canine melanocytic lesions has been recently published by the authors, describing that Cox-2 expression was restricted to the malignant melanoma group, being found in 11 of the 20 cutaneous mali...
CoX is an peripherals library with a unified standard interface specially for ARM Cortex M. - coocox/cox
The beneficial effect of cold atmospheric plasma on parameters of molecules and cell function involved in wound healing in human osteoblast-like cells in v... CAP exposition on osteoblast-like cells caused a significant upregulation of interleukin (IL)-1尾, IL-6, IL-8, tumor necrosis factor ...
Cox回归模型有效地解决了对生存资料进行多因素分析的问题,但是应用Cox回归模型有一个非常重要的前提条件,即比例风险(Proportional hazards)假定,简称PH假定,其 基本假设为:协变量对生存率的影响不随时间的…
AIM: To determine the possible modulating effect of the COX-2 polymorphisms, -765G (rightward arrow) C and -1195A (rightward arrow) G, on the risk of colorectal cancer (CRC) in a Dutch population. METHODS: This case-control study includes 326 patients with CRC and 369 age- and gender...