Morita I. Distinct functions of COX-1 and COX-2. Prostaglandins Other Lipid Mediat. 2002;68 - 69:165-175.Morita I. Distinct functions of COX-1 and COX-2. Prostaglandins Other Lipid Mediat 68-69: 165-175, 2002.Morita I. Distinct functions of COX-1 and COX-2. Prostaglandins Other ...
This chapter focuses on the distinct functions of COX-1 and COX-2. Introduction Prostaglandins are known to be involved in many physiological and pathological processes including inflammation [1], bone resorption [2], ovulation [3], and angiogenesis [4]. Since the discovery of prostaglandin H ...
Distinct functions of COX-1 and COX-2 The enzymes that convert arachidonic acid to prostaglandin H2 are named cyclooxygenase-1 (COX-1) and COX-2. The properties of COX-1 are different from thos... I Morita 被引量: 0发表: 2002年 Distinct isoforms (COX-1 and COX-2) of cyclooxygenase:...
Coupling between cyclooxygenases and terminal prostanoid synthases. Biochem Biophys Res Commun. 2005;338:70–6. Article CAS PubMed Google Scholar Morita I. Distinct functions of COX-1 and COX-2. Prostaglandins Other Lipid Mediat. 2002;68–69:165–75. Article PubMed Google Scholar Kang YJ...
RUNX2 overexpression enhanced antitumor efficacy of mouse CAR T cells, dependent on prior cell state, and heightened human CAR T cell functions. Our data demonstrate that prior antigen experience of CAR T cells determines functional attributes and amenability to transcription factor-mediated functional ...
Taken together, GPx2 and GPx1 have overlapping functions in controlling inflammatory lipid mediator synthesis and, most probably, exert their anti-inflammatory effects by preventing excessive PGE2 production. In view of the high activity of COX and LOX pathways during inflammatory bowel disease our dat...
The efficacy of adoptive T-cell therapies largely depends on the generation of T-cell populations that provide rapid effector function and long-term protective immunity. Yet it is becoming clearer that the phenotypes and functions of T cells are inherently linked to their localization in tissues. ...
Exosomes are communication carriers and suitable biomarker candidates due to their cargoes with specific dynamic profiles. Integrins, as valuable prognostic markers in cancer, have importance in exosome-cell interaction. However, the role of exosome inte
factors as potential targets to augment the function of naive-derived CD8+CAR T cells. RUNX2 overexpression enhanced antitumor efficacy of mouse CAR T cells, dependent on prior cell state, and heightened human CAR T cell functions. Our data demonstrate that prior antigen experience of CAR ...
Figure 2. Morphological and Cytoskeletal Analysis of Three Groups of da Neurons from the Fruit Fly Larva Distributions of dendritic length (A and D), microtubule (B and E), and F-actin (C and F) is examined as functions of path distance from soma (A–C) and Strahler order (D–F) fo...