Whereas the sequences of the 5'- and 3'-UTR of the mRNA templates were not revealed in the literature, the 3'-UTR of BNT162b mRNA vaccine derived empirically by screening naturally occurring 3'-UTRs for the highest RNA stability [75]. On the other hand, CVnCoV and LNP-nCoVsaRNA were...
U.S. National Library of Medicine Safety and Immunogenicity. Study of 2019-nCoV Vaccine (mRNA-1273) to Prevent SARS-CoV-2 Infection (NCT04283461). Available online: https://clinicaltrials.gov/ct2/show/ NCT04283461 (accessed on 21 August 2020). 9. Calder, P.C. Immunonutrition...
COVID-19 mRNA vaccines; myo-pericarditis and COVID-19 mRNA vaccines; multisystem inflammatory syndrome and COVID-19 mRNA vaccines; arrhythmias and COVID-19 mRNA vaccines; pathogenesis of myocarditis following COVID-19 mRNA vaccines; MIS-A; MIS-C; MIS-V; myocarditis; COVID-19 mRNA vaccine ...
The most clinically advanced vaccine developed by Pfizer/BioNTech, BNT162b2 (tozinameran, Comirnaty), is mRNA-based: this technique combines an engineered mRNA vaccination with lipid nanoparticles (LNPs) [3]. The genetic code for the COVID-19 full-length spike protein is provided by the mRNA...
2.1. Messenger RNA (mRNA) Vaccines The Moderna mRNA-1273 [22] and Pfizer/BioNtech BNT162b2 (also known by brand name Comirnaty or by generic name tozinameran) (https://www.fiercepharma.com/marketing/pfizer-biontech-select-comirnaty-as-brand-name-for-covid-19-vaccine(accessed on 9 Februa...