The approved COVID-19 mRNA vaccines and the relevant clinical trials have shown in Table 1. Table 1. List of COVID-19 mRNA vaccines. COVID-19 mRNA vaccineTargetmRNA dose (µg)Ref. mRNA-1273 S-2P 100 [23] CoV3 S 1 [23] Ptx-Covid19-B N.A 16–100 [23] HDT-301 S 1–25 ...
COVID-19 mRNA vaccines; myo-pericarditis and COVID-19 mRNA vaccines; multisystem inflammatory syndrome and COVID-19 mRNA vaccines; arrhythmias and COVID-19 mRNA vaccines; pathogenesis of myocarditis following COVID-19 mRNA vaccines; MIS-A; MIS-C; MIS-V; myocarditis; COVID-19 mRNA vaccine ...
So far, in early COVID-19 trials, mRNA platforms have turned up encouraging results. “Certainly, these vaccines look like they’re generating the immune response that we need, and the reaction profiles have not been associated with severe reactions,” said Kathryn Edwards, MD, scientific direct...
This chapter will cover the development of COVID-19 vaccines with a focus on mRNA-based COVID-19 vaccines. This will include vaccine efficacy from both clinic trials and real-world vaccination studies. The four major SARS-CoV-2 variants of concern (VOC) will also be explored. The impact ...
COVID-19 is caused by severe acute respiratory syndrome coronavirus -2 (SARS-CoV-2), a name adapted from SARS-CoV that caused the infection of SARS in 2003 [2]. Since none of the explored therapies can directly kill the virus, vaccines have become the last hope to stop the pandemic. ...
COVID-19 ‘Vaccines’ Are Gene Therapy Story at-a-glance mRNA “vaccines” created by Moderna and Pfizer are gene therapies. They fulfill all the definitions of gene therapy and none of the definitions for a vaccine. This matters, as you cannot mandate a gene therapy against COVID-19 any...
The research is important because "the world is relying on safe and effective vaccines to bring an end to the COVID-19 pandemic," said Klein, director of the Kaiser Permanente Vaccine Study Center, senior research scientist with the Kaiser Permanente Division of Research, and principal investigato...
QuestionWhat is the immunogenicity of COVID-19 messenger RNA (mRNA) vaccines in pregnant and lactating women? FindingsIn this cohort study involving 103 women who received a COVID-19 mRNA vaccine, 30 of whom were pregnant and 16 of whom were lactating, immunogenicity was demonstrated in all, ...
The 2024-2025 Formula COVID-19 vaccines have been adapted for Omicron KP.2 based on guidance from the FDA, which stated that KP.2 is the preferred strain of the JN.1 lineage for COVID-19 vaccines for use in the U.S. during the 2024-2025 fall and winter season. ...
Duration of effectiveness of the COVID-19 vaccine in Japan: a retrospective cohort study using large-scale population-based registry data Kohei Uemura Sachiko Ono Hideo Yasunaga BMC Infectious Diseases (2024) Current Progress, Challenges and Prospects in the Development of COVID-19 Vaccines Congr...