6月16日,《nature reviews drug discover》杂志发表了一篇题为“Immune status could determine efficacy of COVID-19 therapies”的文章,深度分析了免疫系统对COVID-19治疗效果的影响。 新出现的证据表明,SARS-CoV-2可以驱动一系列不同的...
Mathew D, Giles JR, Baxter AE, et al; UPenn COVID Processing Unit. Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications. Science. Published online July 15, 2020.PubMedGoogle Scholar 5. Le Bert N, Tan AT, Kunasegaran K, et al. SARS-CoV-...
大多数相互作用的节点在不同的细胞类型中有差异表达,特别是在中心显示的密集连接的网线中。 文献来源:Yao, Changfu et al. “Celltype-specific immune dysregulation in severely ill COVID-19 patients.” medRxiv: the preprint server for health sciences 2020.07.23.20...
[5] Qeadan F, Tingey B, Gu L Y , et al. Prognostic Values of Serum Ferritin and D-Dimer Trajectory in Patients with COVID-19[J]. Viruses, 2021, 13(3):419. [6] Henry B M, de Oliveira M H S, Benoit S, et al. Hematologic, biochemical and immune biomarker abnormalities associate...
1#Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19(来源:Nature Medicine) 2#Reinfection could not occur in SARS-CoV-2 infected rhesus macaques(来源:bioRxiv) 3#脑卒中延迟就诊因素分析(来源:心脑血管病防治) ...
今天分享的文献是2020年5月4日,在Cell Discovery杂志上在线发表题为“Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing” 的研究论文。 该文选取了早期恢复阶段(ERS)和晚期恢复阶段(LRS)来自10例COVID-19患者提供的70,858个细胞,以及5个健康供体(HC)的57,238个细胞...
文献来源:Yao, Changfu et al. “Celltype-specific immune dysregulation in severely ill COVID-19 patients.” medRxiv: the preprint server for health sciences 2020.07.23.20161182. 24 Jul. 2020,doi:10.1101/2020.07.23.20161182. Preprint. 原文通讯作者团队 ...
al., SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro. Front Cell Infect Microbiol, 2021. 11: p. 701278.5. Dalskov, L., et al., SARS-CoV-2 evades immune detection in alveolar macrophages. EMBO Rep, 2020. 21(12): p. e51252.想了解更多精彩内容，快来关注BioArt生物艺术 ...
近日来自Columbia University Irving Medical Center和University of Pittsburgh等单位联合发表了题为“Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19”的研究论文,针对COVID-19肺炎患者的肺泡功能障碍导致患者死亡的病理学机制进行了深入探索研究,为后续COVID-19肺炎患者的...
然而依然缺乏充足的临床病例分析以及系统深入的免疫病理学研究。近日,英国多个研究所团队联合开展了一项研究,为理解其中关键的免疫炎症应答基因及时间动态变化提供了更深入的见解,相关结果发表在Science Immunology上,题为“Longitudinal immune profiling reveals key myeloidsignatures associated with COVID-19”。