Neurological symptoms can be difficult to study due to the complexity of the central and peripheral nervous system. These neurologic symptoms can be difficult to identify and quantitate. This narrative review will describe approaches for assessing neurologic manifestations of COVID-19, with examples of...
Li and colleagues (2020) have suggested that SARS-CoV-2 can enter the brain, and it might be the cause of the respiratory failure in patients with COVID-19 [25]. On the other hand, Turtle (2020) has reported that respiratory failure alone does not suggest central nervous system invasion...
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nat Neurosci 24:168–175 (2020). doi: 10.1038/s41593-020-00758-5 [7] Kantonen J, et al. Neuropathologic features of four autopsied COVID-19 patients. Brain Pathol 30: ...
Josephson and Kamel touched a key issue about how SARS-CoV-2 attacks the central nervous system (CNS) (1). Most authors consider that the systemic expression of this disease, such as the cytokine storm, immune-mediated inflammatory syndromes, and hypercoagulability, are responsible for the major...
COVID-19 can affect the central nervous system (CNS) indirectly by inflammatory mechanisms and even directly enter the CNS. Thereby, COVID-19 can evoke a range of neurosensory conditions belonging to infectious, inflammatory, demyelinating, and degenerative classes. A broad range of non-specific ...
The present review discusses the peripheral nervous system (PNS) manifestations associated with coronavirus disease 2019 (COVID-19). Nerve pain and skeleta
6.Lau KK, Yu WC, Chu CM, Lau ST, Sheng B, Yuen KY. Possible central nervous system infection by SARS coronavirus. Emerg Infect Dis2004;10:342-344. 7.Perlman S, Jacobsen G, Afifi A. Spread of a neurotropic mur...
(murine hepatitis virus) that was extensively investigated for its ability to cause persistent infection in the central nervous system also in primates, in some cases associated with demyelination [88,89], several studies have shown that persistent infection of FCoV (feline coronavirus) can often ...
尽管早期SARS-CoV-2可能通过鼻腔和嗅觉途径迁移或通过血脑屏障运输进入中枢神经系统(central nervous system, CNS),对有神经精神症状的患者的脑脊液(cerebrospinal fluid, CSF)进行分析,几乎都无法通过逆转录聚合酶链反应检测病毒RNA。相反,来自CSF和脑组织的多数证据表明,中枢神经系统内的免疫激活和炎症是急性COVID-19神...
Recent publications [[1], [2], [3]] have described neurological manifestations in COVID-19 involving the central nervous system (CNS), peripheral nervous system (PNS) and muscle, as well as early alterations of olfaction and taste [4]. The Environmental Neurology Specialty Group of the World...