1). Thus, an immune-mediated nervous system impairment may occur after a viral infection. Supporting this, the CSF of two patients having COVID-19 encephalopathy showed SARS-CoV-2 antibodies. Through enzyme-linked immunosorbent assay (ELISA), SARS-CoV-2 S and N protein antigens were detected...
Additionally, it summarizes the nervous system diseases and disorders caused by the oral and maxillofacial systems, as well as the complex diseases that are strongly linked to the interaction between the nervous and stomatognathic systems. By gaining a better understanding of these complex scenarios,...
Glial fibrillary acidic protein (GFAP), an intracellular type III intermediate filament protein, provides structural support and maintains the mechanical integrity of astrocytes. It is predominantly found in the astrocytes which are the most abundant sub
Microscopic, membranous vesicles known as extracellular vesicles (EVs) have been proposed to play a role in the mechanisms underlying central nervous system (CNS) diseases. EVs are secreted by a variety of cells, including myeloid, endothelial, microglial, oligodendroglial, and mesenchymal stem cells...
COVID-19 can affect the central nervous system (CNS) indirectly by inflammatory mechanisms and even directly enter the CNS. Thereby, COVID-19 can evoke a r
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS). Astroglia contribute to the pathophysiology of all neurological and neuropsychiatric disorders in ways that can be either beneficial or detrimental to disorder ou...
Almost 10% of the population (or >30 million people in the United States) may acquire an autonomic disorder requiring medical attention. Because the ANS maintains internal physiologic homeostasis, disorders of this system can be present with both central as well as peripheral nervous system localizat...
Future studies using new strategies to isolate novel antibodies not detected by conventional immunohistochemistry will be necessary to increase our knowledge around the immunomic repertoire of the PCD associated with SCLC and provide new tools to improve our diagnostic accuracy of this disorder. Acknow...
Researchers at theUniversity of California San Diego School of Medicinehave conducted an investigation that provides new insights into the causes of spina bifida, the most common structural disorder of the human nervous system. Work of the group, led by Keng Ioi Vong, Ph.D., and San...
Fibromyalgia (FM) is a chronic pain disorder that is understood to result from amplified sensory and pain signaling within the central nervous system. FM afflicts an estimated 6-12 million adults in the U.S.1, approximately 90% of whom are women. Symptoms include chronic widespread pain, non...