%CTLA-4+CD101+ of Treg cells 8.3 ± 6.7 13.6 ± 6.7 <0.0001 %CD39+CD101+ of Treg cells 9.1 ± 8 13.4 ± 8 0.0001 %Ki-67+CD101+ of Treg cells 0.8 ± 0.8 1.3 ± 0.8 <0.0001 Dendritic cell (DC) characteristics %CXCR4+ of CD1c+ DCs 47.4 ± 32.7 58.8 ± 26.6 0.0063 %CXCR4...
such as hepatocytes. (a) In secondary lymphoid organs, DC-mediated T-cell priming results in T-cell expansion and activation of their effector function. In the case of cytolytic T cells, naive CD8+T cells expand after antigen-specific stimulation, exhibit prolonged ...
To permit the successful enrichment of highly pure populations of blood DC, PBMC were first depleted of monocytes using the monocyte specific marker CD1442,43 and the resulting CD14 negative fraction enriched for CD172a+ cells using magnetic-based cell sorting (Fig. 1A). The resulting CD14...
. Low Rab37, low TSP1 expression alone with high angiogenesis marker CD31 in lung cancer patients is associated with poor disease outcome [28]. In addition, secreted frizzled-related protein-1 (SFRP1), an extracellular antagonist of Wnt, is a cargo protein of Rab37 in cancer cells. SFRP1 ...
four DC subsets can be identified: the two classical DC subsets, CD103+and CD103-DCs, the plasmacytoid B220+DCs and hepatic DC precursors.2,85,86The liver is enriched in pDCs. Hepatic DCs can mediate immune tolerance either by direct T-cell depletion, inducing T-cell anergy or inducing ...
Tanaka Y, Yoneda H, Hosokawa M, Miwa T, Yazawa S (2014) Application of marker-assisted selection in breeding of a new fresh pepper cultivar (Capsicum annuum) containing capsinoids, low-pungent capsaicinoid analogs. Sci Hortic 165:242–245 ...
MerTK (Fig.4d), a hallmark receptor of tissue-resident alternatively activated macrophages that promote apoptotic cell clearance and inflammation resolution. Conversely, CD11c+ATMs from WT and Batf3-deficient mice showed comparable expression of CD9 (Fig.4e), a marker of proinflammatory lipid-laden ...
(cMoP)53 and common DC precursors (CDPs).54–56 However, more recently some granulocytic potential of these progenitors has also been described.57 Furthermore, this study demonstrated that, contrary to previous reports, the MDP had limited potential to generate cDCs and pDCs, and that the bi...
Vales MI, Brown CR, Yilma S, Hane DC, James SR, Shock CC, Charlton BA, Karaagac E, Mosley AR, Culp D, Feibert E, Stark JC, Pavek MJ, Knowles NR, Novy RG, Whitworth JL (2012) Purple Pelisse: a specialty ‘fingerling’ potato with purple skin and flesh and medium specific gravi...
Double labeling for the plasma membrane marker WGA (wheat germ agglutinin) or the adherens junction marker β-catenin showed TRPV4-immunoreactivity (TRPV4-ir) to be predominantly expressed across patches of the plasma membrane (Fig. 1c), whereas co-staining with the primary ciliary marker ...