Moreover, a colony-forming assay showed that the development of pSSC colonies was disrupted by a high concentration of lipopolysaccharide. These studies indicated that CD14 is surface marker of early spermatogonia in developing porcine testes and in pSSCs, suggesting a role for CD14 in porcine ...
CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding p...
Conclusions CD163+CD14+ macrophages could be potentially used as an immune diagnostic marker for MPE and has better assay sensitivity than that of cytological analysis. 展开 关键词: Malignant pleural effusion Tumor-associated macrophage CD163 Biomarker Diagnosis ...
CD14 was first identified on the surface of monocytes and macrophages [13] and ever since CD14 has been widely used as a monocyte/macrophage marker. Recently it has become clear that CD14 is also expressed by other cells and not even restricted to the myeloid cell lineage [14]. In mammals...
Identify aldo-keto reductase (AKR) as a tightly regulated human target of NRF2 that can be used as a marker of NRF2 activity (Click to Enlarge) Human Peripheral Blood CD14+ Monocytes: HPBM Details Tissue Normal healthy human peripheral blood QC No bacteria, yeast, fungi, mycoplasma, virus ...
Introduction: Presepsin, a subtype of soluble CD14, is an inflammatory marker, which largely reflects monocyte activation and seems to be a precise diagnostic marker of sepsis. However, its clinical significance remains unclear in cardiovascular disease. This prospective study aimed to investigate the ...
流式细胞术检测CD14 +单核细胞HLA-DR阳性表达和淋巴细胞亚群细胞绝对计数,免疫透射比浊法检测血浆IgG、IgM、IgA水平;酶联免疫吸附试验(ELISA)检测血浆炎症因子IFN-γ和IL-10浓度;小儿危重病例评分(PCIS)及第三代小儿死亡危险评分(PRISM Ⅲ)用于病情评估。 结果(1)普通型、重型和危重型HFMD患儿单核细胞HLA-DR...
3,4,5 Thus, CD14 appears to sit at the apex of TLR4 signaling, required not only for LPS delivery but also for the downstream intracellular signaling, though itself is not a part of the TLR4 signaling complex. Interestingly, CD14 is also a phenotype marker of monocytes, which circulate in...
DC-HIL Receptor Is a Target for Restoring the Suppressed T Cell Response Caused by Myeloid-derived Suppressor Cells in Cancer Patients DC-HIL blockade as a potential treatment for metastatic cancers,with high blood levels of DC-HIL~+ MDSC as a prognostic marker for the best responders... K ...
More importantly, we for the first time find the level of CD14<sup>+</sup>HLA-DR<sup>−/low</sup> is a biological indicator of poor prognosis through the analysis of 3-year overall survival. Furthermore, we evidenced that the proportion of CD14<sup>+</sup>HLA-DR<sup>−/low</...