disorder include blood-vessel inflammation in the form of tiny areas ofnecrosisin the fingertips, chronic legulcersand lesions in the peripheral nerves, inflammation of the pericardium and of the sclerae, inflammation and nodule formation in the lungs and pleura (tissue covering the lungs), anemia...
Polymyositis/dermatomyositis, a systemic connective tissue disorder, is well known to be associated with interstitial lung disease.55,56 Three main clinical presentations are recognized: (1) acute fulminant respiratory distress resembling the so-called Hamman-Rich syndrome, (2) slowly progressive dyspnea...
CONNECTIVE tissue diseasesPULMONARY arterial hypertensionQUALITY of lifeLUNG diseasesLIFE expectancyConnective tissue diseases are a multisystem disorder that can cause impairments in quality of life, shorten life expectancy, and increase the risk of mortality at a younger age. These...
Impairment of renal function is present to some extent in many connective tissue diseases (CTDs) with variable occurrence in Sjögren syndrome [1,2], roughly 5% in systemic scleroderma (SSc) [3], rarely in inflammatory auto-immune myopathies, a prevalence of approximately 50% in systemic lup...
Rheumatoid arthritis decreases life expectancy; however, this effect on mortality has been decreasing over time and appears to be small. One large cohort study found an excess mortality of only approximately 4 months, which was not apparent until 20 years post-diagnosis (1). Respira...
and pseudoxanthoma elasticum. People can also acquire diseases like scurvy, polymyositis, rheumatoidarthritis, and systemiclupuserythematosus. The connective tissue disease symptoms vary, depending on the exact disorder and its severity, and may onset at any time during a patient's life, from infancy ...
Should Endovascular Therapy Be Considered for Patients With Connective Tissue Disorder? Can J Cardiol. 2016 Jan;32(1):1-3.MaudeGagné-Loranger, PierreVoisine, FrançoisDagenais. (2015) Should endovascular therapy be considered for patients with connective tissue disorder?. Canadian Journal of ...
Marfan syndrome is a heritable disorder of the connective tissue that affects the cardiovascular, skeletal and ocular systems, and often involves the skin, nervous system and lungs. Historically, a person with Marfan syndrome had a poor prognosis due to the cardiovascular effects of this disorder. ...