However, its mechanism of action in treating connective tissue diseaserelated (CTD)-ILD remains unclear. Purpose: To investigate the mechanism of tripterine in CTD-ILD treatment by combining network pharmacology and an in vivo experiment. Methods: The related targets of tripteri...
Paul KatzJohn Wiley & Sons, Ltd.Arthritis & RheumatismMitchell, S.R., McCarty, G.A., Katz, P. Anticentromere antibody is not specific for connective tissue disease with a promising prog- nosis. Arthritis Rheum, 1985, 28, 1076-1077....
Connective Tissue: Connective tissue is a type of tissue that supports, protects, and provides structure to the tissue and organs of the body. Dense connective, loose connective, and specialized connective tissue are types of connective tissue. Answer and Explanation: (...
Peyronie's disease is caused by a buildup of scar tissue inside your penis. Scar tissue isn't as flexible as your skin, so it doesn't expand when you get an erection. This causes your penis to curve or bend up, down, or to the side, depending on where the scar tissue is. You m...
摘要: Every doctor in the western world might, at some point in their career, encounter a patient with Dupuytren Disease (DD), also known as the Viking disease. DD is considered to be one of the most common connective tissue disorders in Northern Europe, hence the Nordic link.关键词:...
Brittle bone disease, also called osteogenesis imperfecta, is a genetic connective tissue disorder that is preset at birth and lasts for life. It causes fragile bones that break easily, bones that aren't formed correctly, and other problems that can range from mild to severe. This happens becau...
Mesenchymal stem cells (MSCs) are now known to display not only adult stem cell multipotency but also robust anti-inflammatory and regenerative properties. After widespread in vitro and in vivo preclinical testing in several autoimmune disease models, al
The intrinsic nature of scleritis poses an ultimate challenge to the skill of the managing ophthalmologist. The chronicity of the disease, its tendency to exacerbate and remit, its relationship with many ocular and systemic diseases, and its variable res
et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99, 81–92 (1999). Article CAS PubMed Google Scholar Zhou, Z. et al. Impaired endochondral ossification and angiogenesis in mice deficient in membrane...
IPF is a fatal disease with a median survival time of only 2–4 years from diagnosis (Steele and Schwartz, 2013). The mechanisms and nature of the periphery-to-center progression of IPF are poorly understood, although studies have implicated contributions from dysregulated alveolar type II (AT2...