However, its mechanism of action in treating connective tissue diseaserelated (CTD)-ILD remains unclear. Purpose: To investigate the mechanism of tripterine in CTD-ILD treatment by combining network pharmacology and an in vivo experiment. Methods: The related targets of tripteri...
Paul KatzJohn Wiley & Sons, Ltd.Arthritis & RheumatismMitchell, S.R., McCarty, G.A., Katz, P. Anticentromere antibody is not specific for connective tissue disease with a promising prog- nosis. Arthritis Rheum, 1985, 28, 1076-1077....
Peyronie's disease is caused by a buildup of scar tissue inside your penis. Scar tissue isn't as flexible as your skin, so it doesn't expand when you get an erection. This causes your penis to curve or bend up, down, or to the side, depending on where the scar tissue is. You m...
摘要: Every doctor in the western world might, at some point in their career, encounter a patient with Dupuytren Disease (DD), also known as the Viking disease. DD is considered to be one of the most common connective tissue disorders in Northern Europe, hence the Nordic link.关键词:...
Brittle bone disease, also called osteogenesis imperfecta, is a genetic connective tissue disorder that is preset at birth and lasts for life. It causes fragile bones that break easily, bones that aren't formed correctly, and other problems that can range from mild to severe. This happens becau...
Mesenchymal stem cells (MSCs) are now known to display not only adult stem cell multipotency but also robust anti-inflammatory and regenerative properties. After widespread in vitro and in vivo preclinical testing in several autoimmune disease models, al
The intrinsic nature of scleritis poses an ultimate challenge to the skill of the managing ophthalmologist. The chronicity of the disease, its tendency to exacerbate and remit, its relationship with many ocular and systemic diseases, and its variable res
et al. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99, 81–92 (1999). Article CAS PubMed Google Scholar Zhou, Z. et al. Impaired endochondral ossification and angiogenesis in mice deficient in membrane...
Despite the release of similar mediators during anaphylaxis, mast cells and basophils differ in several ways. Mast cells are more abundant than basophils and generally reside in the connective tissue of subcutaneous and submucosal areas.Basophilscharacteristically circulate in the blood.48Despite these dif...
The U.S. Centers for Disease Control and Prevention notes that the condition can be caused by any one of several possible causes: high blood pressure in the lungs' arteries resulting from certain types of congenital heart disease; connective tissue disease; coronary artery disease; high blood pre...