Cascade testing for autoantibodies in connective tissue diseases. Mayo Clin. Proc. 70, 183 (PubMed: 7845044).Homburger HA. Cascade testing for autoantibodies in connec- tive tissue diseases. Mayo Clin Proc. 1995;70:183---4.Homburger HA. Cascade testing for autoantibodies in connective tissue ...
摘要: Presents answers to questions concerning connective tissue diseases. Undifferentiated connective tissue disease; Characterization of connective tissue diseases; Autoantibodies as diagnostic markers; Concept of mixed connective tissue disease; Treatment and clinical relevance of overlapping syndromes....
HCs indicates healthy controls; RA, rheumatoid arthritis; SLE, Systemic Lupus Erythematosus; pSS, primary Sjogren's syndrome patients; AS, Ankylosing Spondylitis; UCTD, undifferentiated connective tissue diseases patients. BMI, body mass indexes; WBC, white blood cell; RBC, Red blood cell; PLT, pla...
Autoimmune connective tissue diseases are associated with liver abnormalities and often have overlapping pathological and clinical manifestations. As a result, they can present great clinical challenges and evoke questions about diagnostic criteria for liver diseases. Moreover, discriminating between liver invo...
Systemic Connective Tissue Disorders refer to a group of immunologically mediated diseases characterized by inflammation of synovial and serosal membranes, connective tissue, and blood vessels in various tissues, often involving the lungs and leading to pulmonary complications. ...
Connective tissue growth factor (CTGF/CCN2) was considered to have an important role in this process. In this study, we demonstrated that expression of CTGF was significantly upregulated in clinical tissue samples of gastric carcinoma (GC) samples. Forced expression of CTGF in AGS GC cells ...
Connective tissue growth factor: structure-function relationships of a mosaic, multifunctional protein. Growth Factors 2008; 26: 80–91. 5 Shi-Wen X, Leask A, Abraham D. Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis. Cytokine Growth ...
www.nature.com/scientificreports OPEN A virus-like particle-based connective tissue growth factor vaccine suppresses carbon received: 29 June 2015 tetrachloride-induced hepaticaccepted:03August2016 fibrosis in micePublished:26August2016 Shuang Li1,Yi-Fei Lv2, Hou-Qiang Su1, Qian-Nan Zhang...
Connective tissue growth factor (CTGF) overexpression underlies the development of pulmonary fibrosis. Our previous report showed that the Rac1-dependent extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and activator protein (AP)-1 pathways are involved in CXCL12-generated...
IL-1β contributes to connective tissue destruction in part by up-regulating stromelysin-1 (MMP-3), which in fibroblasts is a focal adhesion-dependent process. Protein tyrosine phosphatase-α (PTPα) is enriched in and regulates the formation of focal adhesions, but the role of PTPα in conne...