mixed connective tissue disease 混合结缔组织病 myopathy of connective tissue disease 结缔组织病性肌病 arthritis of connective tissue disease 结缔组织病性关节炎 connective tissue n. 结缔体素,结缔组织 collagenic connective tissue 胶原结缔组织 electric connective tissue 电结缔组织 connective tissue sh...
Summary Mixed connective tissue disease (MCTD) is an overlap syndrome characterized by the combined features of systemic lupus erythematosus, systemic sclerosis, polymyositis, and rheumatoid arthritis, and is associated with high titers of antibody to the U1 nuclear ribonucleoprotein antigen. A prominent ...
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Mixed connective tissue disease (MCTD), or: Sharp syndrome, is an uncommon, specifically defined, overlap syndrome. MCTD should be suspected when additional overlapping features are present in patients appearing to have rheumatoid arthritis, SLE, scleroderma, or polymyositis. MCTD is characterised ...
Mixed connective tissue disease)Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia. Related to Mixed connective tissue disease: polymyositis, Undifferentiated Connective Tissue Diseasedis·ease (dĭ-zēz′) n. 1. An abnormal condition of a part, organ, or system of an organism ...
The etiology of mixed connective tissue disease is a mystery. But as this much is known, that is an autoimmune disorder; that is, it involves the body’s immune system attacking the healthy tissues. When antibodies of the immune system begin to attack the connective tissues that provide the ...
Mixed connective tissue disease (MCTD) was first described in 1972 as a disease syndrome with overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE) and polymyositis associated with antibodies to RNAse sensitive extractable nuclear antigen. When the antigen was subsequently characteri...
Signs and symptoms of mixed connective tissue disease can include rash, muscle pain, joint pain, swollen fingers, swollen hands, and malaise. Other associated symptoms and signs can include low-grade fever and Raynaud's phenomenon (sensitivity, numbness, and loss of color in the fingers, toes,...
Mixed connective tissue disease (MCTD) was first described by Gordon Sharp,1 in 1972, as a distinct connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and dermato/polymyositis (DP/PM). This can be distinguishe...
Mixed Connective Tissue Disease . Figure 1 The U1-RNP complex is composed of the specific U1-RNA stem as well as three specific protein subunits known as the A, C, and 70 kD subunits. Another group of proteins in this structure, ... 展开 ...