Ch 4. Understanding Genetics & DNA Ch 5. Understanding Metabolism Ch 6. Bacterial Biology Morphology of Bacteria | Definition, Shapes & Arrangements 5:58 Bacterial Cytoplasmic Membrane | Components, Structure & Function 8:06 Bacterial Cell Wall Definition, Function & Composition 9:13 Bacterial ...
Cascales E. Definition of a Bacterial Type IV Secretion Pathway for a DNA Substrate. 2004;304(5674):1170-3. Wang P, Yu Z, Li B, Cai X, Zeng Z, Chen X, et al. Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. Microbial Cell Factories. 2015;...
Lederberg’s interests in microbial genetics were furthered when he began medical studies at Columbia where he continued to perform experiments. Having been inspired by Oswald Avery and Colin MacLeod’s discovery of the importance of DNA in 1944, Lederberg began to investigate his hypothesis that, ...
et al. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nature Biotech. 28, 738–742 (2010). CAS Google Scholar Orlicky, S. et al. An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. ...
Modern microbial genetics. 2nd ed. New York: Wiley; 2002. p. 178–225. Google Scholar Hoffman LM, Haskins DJ, Jendrisak J. TypeOne™ inhibitor improves transformation efficiencies by blocking type I restriction and modification systems in vivo. Epicentre Forum. 2002;9:8. Google Scholar ...
In one example, a chemical genetics screen in yeast for enhancers of rapamycin iden- tified an inhibitor of SCFMet30 that directly bound to the F-box adaptor Met30 and diminished its binding to the core cullin–RING complex in vivo. Therefore, inhibition was achieved through the apparent ...
GeneticsreviewssoilThis chapter discusses the method for studying bacterial gene transfer in soil by conjugation and transduction. Soil is unique among microbial habitats in that it is a structured environment with a high solid to water ratio. The discreteness of microhabitats in soil, the ...
In addition to the engineered cysteine conjugation strategy, other methods for site-specific attachment of drugs have been developed. Pfizer demonstrated a new technique for conjugation using microbial transglutaminase to couple an amine-containing drug to an engineered glutamine on the antibody. Transgluta...
Overcoming antibiotic resistance: Is siderophore Trojan horse conjugation an answer to evolving resistance in microbial pathogens?Iron acquisitionSiderophores... K Dhusia,A Bajpai,PW Ramteke - 《Journal of Controlled Release》 被引量: 0发表: 2017年 Overcoming antibiotic resistance: Is siderophore Trojan...
The level of the document is geared to technicians with some background and experience in standard laboratory methods used in microbiology but who have limited knowledge of, and experience in, bacterial genetics, molecular biology, and microbial ecology, especially in soil. Many of the specific ...