Conformational changes in the a-fibrous protein of epidermis. 1. Invest. Dermatol. 60, 21.5-218 (1973).Baden HP, Goldsmith LA, Bonar L. Conformational changes in the a-fibrous protein of epidermis. J Invest Dermatol. 1973;60;215-218....
Changes in the bioactivity of a protein after being adsorbed on a material surface may result from conformational changes of the protein. Unfortunately, however, direct evidence of such conformational changes of proteins adsorbed on a flat material surface is sparse so far. This is because probing ...
Conformational changes in proteins at interfaces: from solution to the interface, and back. Macromol Symp 1999;145:125e36.W. Norde, C.E. Giacomelli, Conformational changes in proteins at interfaces: from solution to the interface, and back, Macromol. Symp. 145 (1999) 125-136....
It is well recognized that the conformations of globular proteins are particularly sensitive to environmental changes and that they may be altered by the binding of specific ligands. As a result, it seems likely that interaction between proteins or between the polypeptide chains of multisubunit protei...
A conformational epitope (CE) in an antigentic protein is composed of amino acid residues that are spatially near each other on the antigen's surface but are separated in sequence; CEs bind their complementary paratopes in B-cell receptors and/or antibod
Protein functioning is usually associated to conformational changes. In the last decades, several researchers have made use of elastic network models to investigate such shape changes, showing that these depend on the protein intrinsic f... D Scaramozzino,G Lacidogna,A Carpinteri 被引量: 0发表...
b Diagram schematically illustrating different mechanisms of drug binding involving protein conformational changes. R and RC denote two different conformations of the protein, the latter requires conformational changes for ligand binding. These may occur by conformational selection (blue path) or by ...
The modeling of the rotatory mechanism performed by the F(1)-ATPase complex during ATP synthesis shows that the beta, but not the alpha subunit, undergoes large conformational changes that depend on the occupancy of the catalytic site. Here we determined by fluorescence spectroscopy the changes in...
This requires the acquisition of measurements in live cells before and after the initiation of apoptosis. We monitor conformational changes in Bax associated with its translocation from the cytosol to the mitochondria resulting from the initiation of apoptosis using staurosporin (STS) in live mouse ...
The effects on the protein conformation from the interaction have been characterized using CD and NMR measurements. This study shows that differences in particle curvature strongly influence the amount of the protein's secondary structure that is perturbed. Particles with a longer diameter allow ...