The concept of ''death trajectory'' describes non-categorical life-threatening conditions of four types: progressive decline to death (e.g., spinal muscular atrophy); intermittent periods of intensive care to maintain quality-of-life (e.g., cystic fibrosis); curative treatment is possible but ...
Unfavorable demographic and behavioral characteristics of patient populations:Patient population characteristics can have significant implications for digitalizing disease management. Some chronic conditions, such as cystic fibrosis, are characteristic of young, proactive, and technically savvy patient ...
Nutritional cues control Pseudomonas aeruginosa multicellular behavior in cystic fibrosis sputum. J. Bacteriol. 189, 8079–8087 (2007). Article CAS Google Scholar Kirchner, S. et al. Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant...
There were insufficient transition observations for sickle cell disease, cystic fibrosis, autism, sarcoidosis and multiple sclerosis (as bimorbidity pairs with diabetes) to be included in the analysis. The model was used to calculate the following five key metrics: lifetime risk of MLTC, median ...
Some domains were similar to those identified in Review 1 (e.g. professionalism; information-sharing/decision-making), others were unique (e.g. supporting parenting; access to additional support). Conclusions Multiple and wide-ranging aspects of the way hospital healthcare is organized and ...
46) this has been shown to be 1/46 and in “Hispanic[s]” 1/125.47 For cystic fibrosis when 32 pathogenic variants were examined among a US population, carrier frequency ranged from 1/28 (“Caucasian”) (This term is no longer used by the journal but is used in the original article...
Quittner ALDiGirolamo AMMichel MEigen H Parental response to cystic fibrosis: a contextual analysis of the diagnostic phase.J Pediatr Psychol.1992;17683- 704Google ScholarCrossref 25. Stein REKJessop DJ Relationship between health status and psychological adjustment among children with chronic conditions...
We thank the members of the Tasmanian cystic fibrosis community for their participation and interest in this study. We acknowledge the contributions of Ms Vicki Carroll to the isolation of CF strains and of Dr Kevin Sanderson to the electron microscopic work. We are also indebted to Mr Richard ...
which highlighted the importance of mutations in the intergenic regions for the adaptation ofP. aeruginosato the conditions of cystic fibrosis lungs [65]. We suggest that changes in the length of intergenic homopolymeric tracts mediate phase variation, giving rise to a plethora of phenotypically distin...
Carrier screening began 50 years ago with screening for conditions that have a high prevalence in defined racial/ethnic groups (e.g., Tay–Sachs disease in the Ashkenazi Jewish population; sickle cell disease in Black individuals). Cystic fibrosis was th