Table 1. Cytotoxic activities of incomptines A (IA) and B (IB) isolated from dichloromethane extract of the aerial parts of Decachaeta incompta. Although the data are limited, a structure-cytotoxicity relationship was established from the CC50 values in the tested leukemia cells and revealed...
(Table 1) showed that all samples had significant antitumor properties on leukemic monocyte lymphoma (LML) with EC50values of 75.0 mg/kg, 2.4 mg/kg, and 1.3 mg/kg forDEDi, incomptine A, and methotrexate, respectively. In the acute oral toxicity test, theDEDihad a LD50of 1134.0 mg/kg, ...