Oral vs Intravenous Ciprofloxacin in the Initial Empirical Management of Severe Pyelonephritis or Complicated Urinary Tract InfectionsThere are few data on the efficacy of oral antibiotics in the initial empirical management of severe forms of urinary tract infection (UTI).In a multicenter, prospective,...
diabetes, a larger number of prior deliveries, and lower socioeconomic status are at higher risk.[115]Without treatment, up to 35% progress to a symptomatic UTI and/or pyelonephritis during the pregnancy.[116]Most studies suggest untreated
Conclusions and Relevance Among patients with complicated UTI, including acute pyelonephritis and growth of a baseline pathogen, meropenem-vaborbactam vs piperacillin-tazobactam resulted in a composite outcome of complete resolution or improvement of symptoms along with microbial eradication that met the non...
Compared with patients concurrently admitted to hospital, fewer on HITH were less than 1 year of age (13% vs. 33%; odds ratio: 0.3; P < 0.01).Conclusions: Selected patients presenting to ED with UTI/pyelonephritis may be treated directly via HITH, including some with underlying conditions ...
A pre-populated, ambulatory antibiotic order panel for UTI was implemented in the Mayo Clinic Enterprise on 5/16/2022. The order panel provides antimicrobial regimens which align with both institutional and national treatment guidelines based on patient comorbidities, complicating factors, and beta-...
Within individual studies, resistance rates were generally higher in hospital-acquired vs community-acquired infections, in recurrent vs non-recurrent UTI, in catheter-associated vs non-catheter-associated UTI, in cUTI vs uUTI, and in pyelonephritis vs cystitis. AMR was higher among UTI isolates ...
More information:Keith S. Kaye et al, Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis,JAMA(2022). DOI: 10.1001/jama.2022.17034 ...